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Torsin A Interacting Protein 1 (TOR1AIP1)

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LAP1B; Lamina Associated Polypeptide 1B

Torsin A Interacting Protein 1 (TOR1AIP1)
CCC S005
HGNC 29456
MGI 3582693
RGD 628851
UniProt Q5JTV8
LAP1B encodes 584 amino acids. The sequence homology between the predicted rat LAP1B and huLAP1B was found to be 73.6%. A topological analysis was carried out by transiently expressing N-terminal GFP fused deletion mutants of huLAP1B in cells. The transmembrane (TM) domain (aa 346-368) is required for the localization of the nuclear and endoplasmic reticulum membrane and that the TM domain and the C-terminal half of the nucleoplasmic domain (aa 190-331) are sufficient for the proper localization of LAP1B.
In contrast, the well-conserved lumenal domain of the nuclear membrane is not required for its topological function. Biochemical analysis showed that huLAP1B is retained within the nucleus via interactions of the nucleoplasmic portion with nuclear components.

Organism species: Homo sapiens (Human)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins RPS005Hu01 Recombinant Torsin A Interacting Protein 1 (TOR1AIP1) Positive Control; Immunogen; SDS-PAGE; WB.
Antibodies n/a Monoclonal Antibody to Torsin A Interacting Protein 1 (TOR1AIP1) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to Torsin A Interacting Protein 1 (TOR1AIP1) Polyclonal Antibody Customized Service Offer
Assay Kits n/a CLIA Kit for Torsin A Interacting Protein 1 (TOR1AIP1) CLIA Kit Customized Service Offer
n/a ELISA Kit for Torsin A Interacting Protein 1 (TOR1AIP1) ELISA Kit Customized Service Offer

Organism species: Mus musculus (Mouse)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a Recombinant Torsin A Interacting Protein 1 (TOR1AIP1) Recombinant Protein Customized Service Offer
Antibodies n/a Monoclonal Antibody to Torsin A Interacting Protein 1 (TOR1AIP1) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to Torsin A Interacting Protein 1 (TOR1AIP1) Polyclonal Antibody Customized Service Offer
Assay Kits n/a CLIA Kit for Torsin A Interacting Protein 1 (TOR1AIP1) CLIA Kit Customized Service Offer
n/a ELISA Kit for Torsin A Interacting Protein 1 (TOR1AIP1) ELISA Kit Customized Service Offer

Organism species: Rattus norvegicus (Rat)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a Recombinant Torsin A Interacting Protein 1 (TOR1AIP1) Recombinant Protein Customized Service Offer
Antibodies n/a Monoclonal Antibody to Torsin A Interacting Protein 1 (TOR1AIP1) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to Torsin A Interacting Protein 1 (TOR1AIP1) Polyclonal Antibody Customized Service Offer
Assay Kits n/a CLIA Kit for Torsin A Interacting Protein 1 (TOR1AIP1) CLIA Kit Customized Service Offer
n/a ELISA Kit for Torsin A Interacting Protein 1 (TOR1AIP1) ELISA Kit Customized Service Offer
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  13. "Glycoproteomics analysis of human liver tissue by combination of multiple enzyme digestion and hydrazide chemistry."J. Proteome Res. 8:651-661(2009) [PubMed] [Europe PMC] [Abstract]
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  18. "Regulation of Torsin ATPases by LAP1 and LULL1."Proc. Natl. Acad. Sci. U.S.A. 110:E1545-1554(2013) [PubMed] [Europe PMC] [Abstract]
  19. "Arresting a Torsin ATPase reshapes the endoplasmic reticulum."J. Biol. Chem. 289:552-564(2014) [PubMed] [Europe PMC] [Abstract]
  20. "An enzyme assisted RP-RPLC approach for in-depth analysis of human liver phosphoproteome."J. Proteomics 96:253-262(2014) [PubMed] [Europe PMC] [Abstract]
  21. "The consensus coding sequences of human breast and colorectal cancers." Science 314:268-274(2006) [PubMed] [Europe PMC] [Abstract]