Encoding over 300 genes, chromosome 18 contains about 76 million bases. Trisomy 18, or Edwards syndrome, is the second most common trisomy after Downs syndrome. Symptoms of Edwards syndrome include low birth weight, a variety of physical development defects, heart deformations and breathing difficulty. Translocation between chromosome 18 and 14 is the most common translocation in cancers, and occurs in follicular lymphomas. Niemann-Pick disease, hereditary hemorrhagic telangiectasia and erythropoietic protoporphyria are associated with chromosome 18.
The TGFβ modulators, Smad2, Smad4 and Smad7 are encoded by chromosome 18. The C18orf56 gene product has been provisionally designated C18orf56 pending further characterization.
Organism species: Homo sapiens (Human)
CATALOG NO. | PRODUCT NAME | APPLICATIONS | |
Proteins | n/a | Recombinant TYMS Opposite Strand Protein (TYMSOS) | Recombinant Protein Customized Service Offer |
Antibodies | n/a | Monoclonal Antibody to TYMS Opposite Strand Protein (TYMSOS) | Monoclonal Antibody Customized Service Offer |
n/a | Polyclonal Antibody to TYMS Opposite Strand Protein (TYMSOS) | Polyclonal Antibody Customized Service Offer | |
Assay Kits | n/a | CLIA Kit for TYMS Opposite Strand Protein (TYMSOS) | CLIA Kit Customized Service Offer |
n/a | ELISA Kit for TYMS Opposite Strand Protein (TYMSOS) | ELISA Kit Customized Service Offer |
- "Complete sequencing and characterization of 21,243 full-length human cDNAs." Nat. Genet. 36:40-45(2004) [PubMed] [Europe PMC] [Abstract]
- "DNA sequence and analysis of human chromosome 18." Nature 437:551-555(2005) [PubMed] [Europe PMC] [Abstract]
- "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]