Vascular endothelial growth factor (VEGF-A) and its family proteins are crucial regulators of blood vessel formation and vascular permeability. Snake venom has recently been shown to be an exogenous source of unique VEGF (known as ), and now, two types of VEGF-F with distinct biochemical properties have been reported. VEGF-Fs (venomtype VEGFs) are highly variable in structure and function among species, in contrast to endogenous tissue-type VEGFs (VEGFAs) of snakes.
Although the structures of tissue-type VEGFs are highly conserved among venomous snake species and even among all vertebrates, including humans, those of venom-type VEGFs are extensively variegated, especially in the regions around receptor-binding loops and C-terminal putative coreceptor-binding regions, indicating that highly frequent variations are located around functionally key regions of the proteins.
Organism species: Pan-species (General)
CATALOG NO. | PRODUCT NAME | APPLICATIONS | |
Proteins | n/a | Recombinant Vascular Endothelial Growth Factor F (VEGFF) | Recombinant Protein Customized Service Offer |
Antibodies | n/a | Monoclonal Antibody to Vascular Endothelial Growth Factor F (VEGFF) | Monoclonal Antibody Customized Service Offer |
n/a | Polyclonal Antibody to Vascular Endothelial Growth Factor F (VEGFF) | Polyclonal Antibody Customized Service Offer | |
Assay Kits | n/a | CLIA Kit for Vascular Endothelial Growth Factor F (VEGFF) | CLIA Kit Customized Service Offer |
n/a | ELISA Kit for Vascular Endothelial Growth Factor F (VEGFF) | ELISA Kit Customized Service Offer |