Certain integrins can also bind to soluble ligands such as Fibrinogen, or to counter-receptors on adjacent cells such as the intracellular adhesion molecules (ICAMs), leading to aggregation of cells. Ligands serve to cross-link or cluster integrins by binding to adjacent integrin receptors; both receptor clustering and ligand occupancy are necessary for the activation of integrin-mediated responses. In addition to mediating cell adhesion and cytoskeletal organization, integrins function as signaling receptors. Signals transduced by integrins play a role in many biological processes, including cell growth, differentiation, migration and apoptosis. (integrin-α FG-GAP repeat-containing protein 2) is a 447 amino acid protein that contains two FG-GAP repeats, a motif commonly found in integrin proteins.
Organism species: Homo sapiens (Human)
CATALOG NO. | PRODUCT NAME | APPLICATIONS | |
Proteins | n/a | Recombinant Integrin Alpha FG GAP Repeat Containing Protein 2 (ITFG2) | Recombinant Protein Customized Service Offer |
Antibodies | n/a | Monoclonal Antibody to Integrin Alpha FG GAP Repeat Containing Protein 2 (ITFG2) | Monoclonal Antibody Customized Service Offer |
n/a | Polyclonal Antibody to Integrin Alpha FG GAP Repeat Containing Protein 2 (ITFG2) | Polyclonal Antibody Customized Service Offer | |
Assay Kits | n/a | CLIA Kit for Integrin Alpha FG GAP Repeat Containing Protein 2 (ITFG2) | CLIA Kit Customized Service Offer |
n/a | ELISA Kit for Integrin Alpha FG GAP Repeat Containing Protein 2 (ITFG2) | ELISA Kit Customized Service Offer |
Organism species: Mus musculus (Mouse)
CATALOG NO. | PRODUCT NAME | APPLICATIONS | |
Proteins | n/a | Recombinant Integrin Alpha FG GAP Repeat Containing Protein 2 (ITFG2) | Recombinant Protein Customized Service Offer |
Antibodies | n/a | Monoclonal Antibody to Integrin Alpha FG GAP Repeat Containing Protein 2 (ITFG2) | Monoclonal Antibody Customized Service Offer |
n/a | Polyclonal Antibody to Integrin Alpha FG GAP Repeat Containing Protein 2 (ITFG2) | Polyclonal Antibody Customized Service Offer | |
Assay Kits | n/a | CLIA Kit for Integrin Alpha FG GAP Repeat Containing Protein 2 (ITFG2) | CLIA Kit Customized Service Offer |
n/a | ELISA Kit for Integrin Alpha FG GAP Repeat Containing Protein 2 (ITFG2) | ELISA Kit Customized Service Offer |
Organism species: Rattus norvegicus (Rat)
CATALOG NO. | PRODUCT NAME | APPLICATIONS | |
Proteins | n/a | Recombinant Integrin Alpha FG GAP Repeat Containing Protein 2 (ITFG2) | Recombinant Protein Customized Service Offer |
Antibodies | n/a | Monoclonal Antibody to Integrin Alpha FG GAP Repeat Containing Protein 2 (ITFG2) | Monoclonal Antibody Customized Service Offer |
n/a | Polyclonal Antibody to Integrin Alpha FG GAP Repeat Containing Protein 2 (ITFG2) | Polyclonal Antibody Customized Service Offer | |
Assay Kits | n/a | CLIA Kit for Integrin Alpha FG GAP Repeat Containing Protein 2 (ITFG2) | CLIA Kit Customized Service Offer |
n/a | ELISA Kit for Integrin Alpha FG GAP Repeat Containing Protein 2 (ITFG2) | ELISA Kit Customized Service Offer |
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- "Initial characterization of the human central proteome."BMC Syst. Biol. 5:17-17(2011) [PubMed] [Europe PMC] [Abstract]