Acyl Malonyl Condensing Enzyme 1 Like Protein 2 (AMAC1L2)

AMAC1L2 seems to be intronless. It has high sequence similarity to the gene encoding acyl-malonyl condensing enzyme on chromosome 17. Expressed in placenta and testis. The gene encoding this protein appears to have arisen by SVA-mediated retrotransposition of the AMAC1L3 gene in the primate lineage.

AMAC1L2 is similar to mouse AMAC1, one of the enzymes in the biosynthesis of long-chain fatty acids. AMAC1L2 consists of a single exon and a 3′-polyadeneylation tract present in the genomic DNA adjacent to AMAC1L2, which are characteristics of pseudogenes. In the human genome, three additional sequences coding for elements of AMAC1L2 are located on 17p13.1, 18p11.2 and 17q11.2. Transcript of AMAC1L2 is detected in various tissues: however, whether AMAC1L2 is translated into protein has not been elucidated.