Acyl Malonyl Condensing Enzyme 1 Like Protein 3 (AMAC1L3)

The search resulted in the identification of a single AMAC locus in all four species examined, and it was orthologous to the human AMAC1L3. The murine AMAC1 gene contains two exons similar to human AMAC1L3 gene. Only the human AMAC1L3 locus was colinear with the mouse AMAC1 genomic sequence, whereas the three SVA transduced loci were colinear with the mouse AMAC1 mRNA sequence.

PCR and DNA sequence analyses showed that the intron-containing locus AMAC1L3 is present in all species examined. AMAC1L3 at the inferred source locus had two exons separated by an intron, whereas the three SVA transduced loci contained intronless versions of AMAC1L3. AMAC1, AMAC1L2, and AMAC1L3 were expressed in testis, whereas only AMAC1L2 and AMAC1L3 were expressed in placenta.