Protease, Serine Like Protein 1 (PRSSL1)
[Edit]PROTEASE; PRSS57; SERINE-LIKE, 1; Serine protease 57
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PRSSL1, Belongs to the peptidase S1 family. Contains 1 peptidase S1 domain. PRSSL1 encodes a 30.14-kD secreted protein that shares 34 to 42% amino acid identity with several serine protease families. PRSSL1 is expressed in normal and immortalized nontumorigenic mammary epithelial cells but is reduced or absent in numerous human breast cancer cell lines. Thus, PRSSL1 may play a role in suppression of tumorigenesis.
By fluorescence in situ hybridization, Polikoff et al. (1997) mapped the PRSSL1 gene to 19q13.3. Loss of heterozygosity studies on gliomas showed frequent allelic loss and a commonly deleted region at 19q13.2-q13.4, suggesting the presence of a tumor suppressor gene.
Organism species: Homo sapiens (Human)
| CATALOG NO. | PRODUCT NAME | APPLICATIONS | |
| Proteins | n/a | Recombinant Protease, Serine Like Protein 1 (PRSSL1) | Recombinant Protein Customized Service Offer |
| Antibodies | n/a | Monoclonal Antibody to Protease, Serine Like Protein 1 (PRSSL1) | Monoclonal Antibody Customized Service Offer |
| n/a | Polyclonal Antibody to Protease, Serine Like Protein 1 (PRSSL1) | Polyclonal Antibody Customized Service Offer | |
| Assay Kits | n/a | CLIA Kit for Protease, Serine Like Protein 1 (PRSSL1) | CLIA Kit Customized Service Offer |
| n/a | ELISA Kit for Protease, Serine Like Protein 1 (PRSSL1) | ELISA Kit Customized Service Offer |
Organism species: Mus musculus (Mouse)
| CATALOG NO. | PRODUCT NAME | APPLICATIONS | |
| Proteins | n/a | Recombinant Protease, Serine Like Protein 1 (PRSSL1) | Recombinant Protein Customized Service Offer |
| Antibodies | n/a | Monoclonal Antibody to Protease, Serine Like Protein 1 (PRSSL1) | Monoclonal Antibody Customized Service Offer |
| n/a | Polyclonal Antibody to Protease, Serine Like Protein 1 (PRSSL1) | Polyclonal Antibody Customized Service Offer | |
| Assay Kits | n/a | CLIA Kit for Protease, Serine Like Protein 1 (PRSSL1) | CLIA Kit Customized Service Offer |
| n/a | ELISA Kit for Protease, Serine Like Protein 1 (PRSSL1) | ELISA Kit Customized Service Offer |
Organism species: Rattus norvegicus (Rat)
| CATALOG NO. | PRODUCT NAME | APPLICATIONS | |
| Proteins | n/a | Recombinant Protease, Serine Like Protein 1 (PRSSL1) | Recombinant Protein Customized Service Offer |
| Antibodies | n/a | Monoclonal Antibody to Protease, Serine Like Protein 1 (PRSSL1) | Monoclonal Antibody Customized Service Offer |
| n/a | Polyclonal Antibody to Protease, Serine Like Protein 1 (PRSSL1) | Polyclonal Antibody Customized Service Offer | |
| Assay Kits | n/a | CLIA Kit for Protease, Serine Like Protein 1 (PRSSL1) | CLIA Kit Customized Service Offer |
| n/a | ELISA Kit for Protease, Serine Like Protein 1 (PRSSL1) | ELISA Kit Customized Service Offer |
- "The secreted protein discovery initiative (SPDI), a large-scale effort to identify novel human secreted and transmembrane proteins: a bioinformatics assessment." Genome Res. 13:2265-2270(2003) [PubMed] [Europe PMC] [Abstract]
- "The DNA sequence and biology of human chromosome 19." Nature 428:529-535(2004) [PubMed] [Europe PMC] [Abstract]
- "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]