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TLCD2 is encoded by a gene mapping to human chromosome 17. Chromosome 17 makes up over 2.5% of the human genome with about 81 million bases encoding over 1,200 genes. Two key tumor suppressor genes are associated with chromosome 17, namely, p53 and BRCA1. Tumor suppressor p53 is necessary for maintenance of cellular genetic integrity by moderating cell fate through DNA repair versus cell death. Malfunction or loss of p53 expression is associated with malignant cell growth and Li-Fraumeni syndrome. Like p53, BRCA1 is directly involved in DNA repair, though specifically it is recognized as a genetic determinant of early onset breast cancer and predisposition to cancers of the ovary, colon, prostate gland and fallopian tubes.
Organism species: Homo sapiens (Human)
| CATALOG NO. | PRODUCT NAME | APPLICATIONS | |
| Proteins | n/a | Recombinant TLC Domain Containing Protein 2 (TLCD2) | Recombinant Protein Customized Service Offer |
| Antibodies | n/a | Monoclonal Antibody to TLC Domain Containing Protein 2 (TLCD2) | Monoclonal Antibody Customized Service Offer |
| n/a | Polyclonal Antibody to TLC Domain Containing Protein 2 (TLCD2) | Polyclonal Antibody Customized Service Offer | |
| Assay Kits | n/a | CLIA Kit for TLC Domain Containing Protein 2 (TLCD2) | CLIA Kit Customized Service Offer |
| n/a | ELISA Kit for TLC Domain Containing Protein 2 (TLCD2) | ELISA Kit Customized Service Offer |
Organism species: Mus musculus (Mouse)
| CATALOG NO. | PRODUCT NAME | APPLICATIONS | |
| Proteins | n/a | Recombinant TLC Domain Containing Protein 2 (TLCD2) | Recombinant Protein Customized Service Offer |
| Antibodies | n/a | Monoclonal Antibody to TLC Domain Containing Protein 2 (TLCD2) | Monoclonal Antibody Customized Service Offer |
| n/a | Polyclonal Antibody to TLC Domain Containing Protein 2 (TLCD2) | Polyclonal Antibody Customized Service Offer | |
| Assay Kits | n/a | CLIA Kit for TLC Domain Containing Protein 2 (TLCD2) | CLIA Kit Customized Service Offer |
| n/a | ELISA Kit for TLC Domain Containing Protein 2 (TLCD2) | ELISA Kit Customized Service Offer |
Organism species: Rattus norvegicus (Rat)
| CATALOG NO. | PRODUCT NAME | APPLICATIONS | |
| Proteins | n/a | Recombinant TLC Domain Containing Protein 2 (TLCD2) | Recombinant Protein Customized Service Offer |
| Antibodies | n/a | Monoclonal Antibody to TLC Domain Containing Protein 2 (TLCD2) | Monoclonal Antibody Customized Service Offer |
| n/a | Polyclonal Antibody to TLC Domain Containing Protein 2 (TLCD2) | Polyclonal Antibody Customized Service Offer | |
| Assay Kits | n/a | CLIA Kit for TLC Domain Containing Protein 2 (TLCD2) | CLIA Kit Customized Service Offer |
| n/a | ELISA Kit for TLC Domain Containing Protein 2 (TLCD2) | ELISA Kit Customized Service Offer |
- "DNA sequence of human chromosome 17 and analysis of rearrangement in the human lineage." Nature 440:1045-1049(2006) [PubMed] [Europe PMC] [Abstract]