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Jumonji Domain Containing Protein 7 (JMJD7)

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JmjC domain-containing protein 7

Jumonji Domain Containing Protein 7 (JMJD7)
CCC S406
HGNC 34397
MGI 3845785
PubMed 24467814
UniProt P0C870
A crucial regulator of chromatin dynamics and DNA transcription is the covalent modification and methylation of histones. Generally, methylation of certain lysine residues on Histone H3 and Histone H4 can be associated with transcriptionally active or inactive chromatin.
JMJD7 is a member of a family of JMJC domain-containing histone demethylases that are directly involved in removing methyl residues from distinct and unique lysine residues. These actions are implicated in gene expression and the regulation of cell senescence. JMJC domain-containing histone demethylases are also likely involved in development via their ability to regulate gene expression. JMJD7 contains one JMJC domain and was originally thought to be an alternatively spliced isoform of PLA2G4B.

Organism species: Homo sapiens (Human)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a Recombinant Jumonji Domain Containing Protein 7 (JMJD7) Recombinant Protein Customized Service Offer
Antibodies n/a Monoclonal Antibody to Jumonji Domain Containing Protein 7 (JMJD7) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to Jumonji Domain Containing Protein 7 (JMJD7) Polyclonal Antibody Customized Service Offer
Assay Kits n/a CLIA Kit for Jumonji Domain Containing Protein 7 (JMJD7) CLIA Kit Customized Service Offer
n/a ELISA Kit for Jumonji Domain Containing Protein 7 (JMJD7) ELISA Kit Customized Service Offer

Organism species: Mus musculus (Mouse)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a Recombinant Jumonji Domain Containing Protein 7 (JMJD7) Recombinant Protein Customized Service Offer
Antibodies n/a Monoclonal Antibody to Jumonji Domain Containing Protein 7 (JMJD7) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to Jumonji Domain Containing Protein 7 (JMJD7) Polyclonal Antibody Customized Service Offer
Assay Kits n/a CLIA Kit for Jumonji Domain Containing Protein 7 (JMJD7) CLIA Kit Customized Service Offer
n/a ELISA Kit for Jumonji Domain Containing Protein 7 (JMJD7) ELISA Kit Customized Service Offer
  1. "Complete sequencing and characterization of 21,243 full-length human cDNAs." Nat. Genet. 36:40-45(2004) [PubMed] [Europe PMC] [Abstract]
  2. "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
  3. "Diagnostic exome sequencing in persons with severe intellectual disability."N. Engl. J. Med. 367:1921-1929(2012) [PubMed] [Europe PMC] [Abstract]