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Zinc Finger, SWIM-Type Containing Protein 2 (ZSWIM2)

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ZZZ2; MEX; ZZ-type zinc finger-containing protein 2; MEKK1-related protein X; E3 ubiquitin-protein ligase ZSWIM2

Zinc Finger, SWIM-Type Containing Protein 2 (ZSWIM2)
CCC S517
HGNC 30990
MGI 1919111
PubMed 16522193
RGD 1311373
UniProt Q8NEG5
ZSWIM2, Contains 2 RING-type zinc fingers.Contains 1 SWIM-type zinc finger.Contains 1 ZZ-type zinc finger. E3 ubiquitin-protein ligase involved in the regulation of Fas-, DR3- and DR4-mediated apoptosis. Functions in conjunction with the UBE2D1, UBE2D3 and UBE2E1 E2 ubiquitin-conjugating enzymes
ZSWIM2 is expressed at low level, only 16.6% of the average gene in this release.The gene contains 10 different gt-ag introns. Transcription produces 4 different mRNAs, 3 alternatively spliced variants and 1 unspliced form. There are 2 probable alternative promotors, 3 non overlapping alternative last exons and 3 validated alternative polyadenylation sites. The mRNAs appear to differ by truncation of the 5' end, truncation of the 3' end.

Organism species: Homo sapiens (Human)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a Recombinant Zinc Finger, SWIM-Type Containing Protein 2 (ZSWIM2) Recombinant Protein Customized Service Offer
Antibodies n/a Monoclonal Antibody to Zinc Finger, SWIM-Type Containing Protein 2 (ZSWIM2) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to Zinc Finger, SWIM-Type Containing Protein 2 (ZSWIM2) Polyclonal Antibody Customized Service Offer
Assay Kits n/a CLIA Kit for Zinc Finger, SWIM-Type Containing Protein 2 (ZSWIM2) CLIA Kit Customized Service Offer
n/a ELISA Kit for Zinc Finger, SWIM-Type Containing Protein 2 (ZSWIM2) ELISA Kit Customized Service Offer

Organism species: Mus musculus (Mouse)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a Recombinant Zinc Finger, SWIM-Type Containing Protein 2 (ZSWIM2) Recombinant Protein Customized Service Offer
Antibodies n/a Monoclonal Antibody to Zinc Finger, SWIM-Type Containing Protein 2 (ZSWIM2) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to Zinc Finger, SWIM-Type Containing Protein 2 (ZSWIM2) Polyclonal Antibody Customized Service Offer
Assay Kits n/a CLIA Kit for Zinc Finger, SWIM-Type Containing Protein 2 (ZSWIM2) CLIA Kit Customized Service Offer
n/a ELISA Kit for Zinc Finger, SWIM-Type Containing Protein 2 (ZSWIM2) ELISA Kit Customized Service Offer

Organism species: Rattus norvegicus (Rat)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a Recombinant Zinc Finger, SWIM-Type Containing Protein 2 (ZSWIM2) Recombinant Protein Customized Service Offer
Antibodies n/a Monoclonal Antibody to Zinc Finger, SWIM-Type Containing Protein 2 (ZSWIM2) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to Zinc Finger, SWIM-Type Containing Protein 2 (ZSWIM2) Polyclonal Antibody Customized Service Offer
Assay Kits n/a CLIA Kit for Zinc Finger, SWIM-Type Containing Protein 2 (ZSWIM2) CLIA Kit Customized Service Offer
n/a ELISA Kit for Zinc Finger, SWIM-Type Containing Protein 2 (ZSWIM2) ELISA Kit Customized Service Offer
  1. "Complete sequencing and characterization of 21,243 full-length human cDNAs." Nat. Genet. 36:40-45(2004) [PubMed] [Europe PMC] [Abstract]
  2. "Generation and annotation of the DNA sequences of human chromosomes 2 and 4." Nature 434:724-731(2005) [PubMed] [Europe PMC] [Abstract]
  3. "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
  4. "Solution structure of the ZZ domain of zinc finger SWIM domain containing protein 2."Submitted (FEB-2009) to the PDB data bank