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Tigger Transposable Element Derived Protein 6 (TIGD6)

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Tigger Transposable Element Derived Protein 6 (TIGD6)
CCC S559
HGNC 18332
UniProt Q17RP2
TIGD6 belongs to the tigger subfamily of the pogo superfamily of DNA-mediated transposons in humans. These proteins are related to DNA transposons found in fungi and nematodes, and more distantly to the Tc1 and mariner transposases. They are also very similar to the major mammalian centromere protein B. TIGD3, TIGD4, and TIGD6 seem most closely related to CENP-B (see below), and, like CENP-B, they are widely distributed and highly conserved in mammals.Within a given mammalian genome, TIGD6 is consistently the closest relative to CENP-B, with an average pairwise amino acid identity of 28%.Phylogenetic distance analysis based on synonymous sites with an application of an average neutral substitution rate of ;2.29 in mammals is indicative of a coalescence time congruent with a much earlier divergence of CENP-B, TIGD3, TIGD4, and TIGD6

Organism species: Homo sapiens (Human)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a Recombinant Tigger Transposable Element Derived Protein 6 (TIGD6) Recombinant Protein Customized Service Offer
Antibodies n/a Monoclonal Antibody to Tigger Transposable Element Derived Protein 6 (TIGD6) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to Tigger Transposable Element Derived Protein 6 (TIGD6) Polyclonal Antibody Customized Service Offer
Assay Kits n/a CLIA Kit for Tigger Transposable Element Derived Protein 6 (TIGD6) CLIA Kit Customized Service Offer
n/a ELISA Kit for Tigger Transposable Element Derived Protein 6 (TIGD6) ELISA Kit Customized Service Offer
  1. "Towards a catalog of human genes and proteins: sequencing and analysis of 500 novel complete protein coding human cDNAs." Genome Res. 11:422-435(2001) [PubMed] [Europe PMC] [Abstract]
  2. "Complete sequencing and characterization of 21,243 full-length human cDNAs." Nat. Genet. 36:40-45(2004) [PubMed] [Europe PMC] [Abstract]
  3. "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]