The tetratricopeptide repeat (TPR) motif is a degenerate, 34 amino acid sequence found in many proteins and acts to mediate protein-protein interactions in various pathways. At the sequence level, there can be up to sixteen tandem TPR repeats, each of which has a helix-turn-helix shape that stacks on other TPR repeats to achieve ligand binding specificity.
TTC6 (Tetratricopeptide repeat protein 6) is a 520 amino acid protein that contains thirteen TPR repeats. The gene encoding TTC6 maps to human chromosome 14, which houses over 700 genes and comprises nearly 3.5% of the human genome. Chromosome 14 encodes the presinilin 1 (PSEN1) gene, which is one of the three key genes associated with the development of Alzheimer’s disease (AD).
Organism species: Homo sapiens (Human)
CATALOG NO. | PRODUCT NAME | APPLICATIONS | |
Proteins | n/a | Recombinant Tetratricopeptide Repeat Domain Protein 6 (TTC6) | Recombinant Protein Customized Service Offer |
Antibodies | n/a | Monoclonal Antibody to Tetratricopeptide Repeat Domain Protein 6 (TTC6) | Monoclonal Antibody Customized Service Offer |
n/a | Polyclonal Antibody to Tetratricopeptide Repeat Domain Protein 6 (TTC6) | Polyclonal Antibody Customized Service Offer | |
Assay Kits | n/a | CLIA Kit for Tetratricopeptide Repeat Domain Protein 6 (TTC6) | CLIA Kit Customized Service Offer |
n/a | ELISA Kit for Tetratricopeptide Repeat Domain Protein 6 (TTC6) | ELISA Kit Customized Service Offer |
Organism species: Mus musculus (Mouse)
CATALOG NO. | PRODUCT NAME | APPLICATIONS | |
Proteins | n/a | Recombinant Tetratricopeptide Repeat Domain Protein 6 (TTC6) | Recombinant Protein Customized Service Offer |
Antibodies | n/a | Monoclonal Antibody to Tetratricopeptide Repeat Domain Protein 6 (TTC6) | Monoclonal Antibody Customized Service Offer |
n/a | Polyclonal Antibody to Tetratricopeptide Repeat Domain Protein 6 (TTC6) | Polyclonal Antibody Customized Service Offer | |
Assay Kits | n/a | CLIA Kit for Tetratricopeptide Repeat Domain Protein 6 (TTC6) | CLIA Kit Customized Service Offer |
n/a | ELISA Kit for Tetratricopeptide Repeat Domain Protein 6 (TTC6) | ELISA Kit Customized Service Offer |
Organism species: Rattus norvegicus (Rat)
CATALOG NO. | PRODUCT NAME | APPLICATIONS | |
Proteins | n/a | Recombinant Tetratricopeptide Repeat Domain Protein 6 (TTC6) | Recombinant Protein Customized Service Offer |
Antibodies | n/a | Monoclonal Antibody to Tetratricopeptide Repeat Domain Protein 6 (TTC6) | Monoclonal Antibody Customized Service Offer |
n/a | Polyclonal Antibody to Tetratricopeptide Repeat Domain Protein 6 (TTC6) | Polyclonal Antibody Customized Service Offer | |
Assay Kits | n/a | CLIA Kit for Tetratricopeptide Repeat Domain Protein 6 (TTC6) | CLIA Kit Customized Service Offer |
n/a | ELISA Kit for Tetratricopeptide Repeat Domain Protein 6 (TTC6) | ELISA Kit Customized Service Offer |
- "The DNA sequence and analysis of human chromosome 14." Nature 421:601-607(2003) [PubMed] [Europe PMC] [Abstract]
- "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]