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SET Domain Containing Protein 3 (SETD3)

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C14orf154; Histone-lysine N-methyltransferase setd3

SET Domain Containing Protein 3 (SETD3)
CCC S586
HGNC 20493
MGI 1289184
PubMed 23065515
RGD 1309550
UniProt Q86TU7
SETD3contains 1 SET domain. Proteins bearing the widely distributed SET domain have been shown to methylate lysine residues in histones and other proteins. The structures reveal novel folds for several new domains, including SET, and provide early insights into mechanisms of catalysis and molecular recognition in this family of enzymes. Chromosome 3 is made up of about 214 million bases encoding over 1,100 genes. Notably, there is a chemokine receptor gene cluster and a variety of human cancer related loci on chromosome 3. Particular regions of the chromosome 3 short arm are deleted in many types of cancer cells. Key tumor suppressing genes on chromosome 3 encode apoptosis mediator RASSF1, cell migration regulator HYAL1, and angiogenesis suppressor SEMA3B.

Organism species: Homo sapiens (Human)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a Recombinant SET Domain Containing Protein 3 (SETD3) Recombinant Protein Customized Service Offer
Antibodies n/a Monoclonal Antibody to SET Domain Containing Protein 3 (SETD3) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to SET Domain Containing Protein 3 (SETD3) Polyclonal Antibody Customized Service Offer
Assay Kits n/a CLIA Kit for SET Domain Containing Protein 3 (SETD3) CLIA Kit Customized Service Offer
n/a ELISA Kit for SET Domain Containing Protein 3 (SETD3) ELISA Kit Customized Service Offer

Organism species: Mus musculus (Mouse)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a Recombinant SET Domain Containing Protein 3 (SETD3) Recombinant Protein Customized Service Offer
Antibodies n/a Monoclonal Antibody to SET Domain Containing Protein 3 (SETD3) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to SET Domain Containing Protein 3 (SETD3) Polyclonal Antibody Customized Service Offer
Assay Kits n/a CLIA Kit for SET Domain Containing Protein 3 (SETD3) CLIA Kit Customized Service Offer
n/a ELISA Kit for SET Domain Containing Protein 3 (SETD3) ELISA Kit Customized Service Offer

Organism species: Rattus norvegicus (Rat)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a Recombinant SET Domain Containing Protein 3 (SETD3) Recombinant Protein Customized Service Offer
Antibodies n/a Monoclonal Antibody to SET Domain Containing Protein 3 (SETD3) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to SET Domain Containing Protein 3 (SETD3) Polyclonal Antibody Customized Service Offer
Assay Kits n/a CLIA Kit for SET Domain Containing Protein 3 (SETD3) CLIA Kit Customized Service Offer
n/a ELISA Kit for SET Domain Containing Protein 3 (SETD3) ELISA Kit Customized Service Offer
  1. "Complete sequencing and characterization of 21,243 full-length human cDNAs." Nat. Genet. 36:40-45(2004) [PubMed] [Europe PMC] [Abstract]
  2. "The DNA sequence and analysis of human chromosome 14." Nature 421:601-607(2003) [PubMed] [Europe PMC] [Abstract]
  3. "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
  4. "The full-ORF clone resource of the German cDNA consortium."BMC Genomics 8:399-399(2007) [PubMed] [Europe PMC] [Abstract]
  5. "A quantitative atlas of mitotic phosphorylation."Proc. Natl. Acad. Sci. U.S.A. 105:10762-10767(2008) [PubMed] [Europe PMC] [Abstract]
  6. "Initial characterization of the human central proteome."BMC Syst. Biol. 5:17-17(2011) [PubMed] [Europe PMC] [Abstract]