DEAD Box Polypeptide 46 (DDX46)
[Edit]PRPF5; Prp5; Asp-Glu-Ala-Asp Box Polypeptide 46; Probable ATP-dependent RNA helicase DDX46
DDX46 encodes a member of the DEAD box protein family. DEAD box proteins, characterized by the conserved motif Asp-Glu-Ala-Asp (DEAD), are putative RNA helicases. They are implicated in a number of cellular processes involving alteration of RNA secondary structure, such as translation initiation, nuclear and mitochondrial splicing, and ribosome and spliceosome assembly. Based on their distribution patterns, some members of this family are believed to be involved in embryogenesis, spermatogenesis, and cellular growth and division.
DDX46is a component of the 17S U2 snRNP complex; it plays an important role in pre-mRNA splicing. plays an essential role in splicing, either prior to, or during splicing A complex formation.
Organism species: Homo sapiens (Human)
CATALOG NO. | PRODUCT NAME | APPLICATIONS | |
Proteins | n/a | Recombinant DEAD Box Polypeptide 46 (DDX46) | Recombinant Protein Customized Service Offer |
Antibodies | n/a | Monoclonal Antibody to DEAD Box Polypeptide 46 (DDX46) | Monoclonal Antibody Customized Service Offer |
n/a | Polyclonal Antibody to DEAD Box Polypeptide 46 (DDX46) | Polyclonal Antibody Customized Service Offer | |
Assay Kits | n/a | CLIA Kit for DEAD Box Polypeptide 46 (DDX46) | CLIA Kit Customized Service Offer |
n/a | ELISA Kit for DEAD Box Polypeptide 46 (DDX46) | ELISA Kit Customized Service Offer |
Organism species: Mus musculus (Mouse)
CATALOG NO. | PRODUCT NAME | APPLICATIONS | |
Proteins | n/a | Recombinant DEAD Box Polypeptide 46 (DDX46) | Recombinant Protein Customized Service Offer |
Antibodies | n/a | Monoclonal Antibody to DEAD Box Polypeptide 46 (DDX46) | Monoclonal Antibody Customized Service Offer |
n/a | Polyclonal Antibody to DEAD Box Polypeptide 46 (DDX46) | Polyclonal Antibody Customized Service Offer | |
Assay Kits | n/a | CLIA Kit for DEAD Box Polypeptide 46 (DDX46) | CLIA Kit Customized Service Offer |
n/a | ELISA Kit for DEAD Box Polypeptide 46 (DDX46) | ELISA Kit Customized Service Offer |
Organism species: Rattus norvegicus (Rat)
CATALOG NO. | PRODUCT NAME | APPLICATIONS | |
Proteins | n/a | Recombinant DEAD Box Polypeptide 46 (DDX46) | Recombinant Protein Customized Service Offer |
Antibodies | n/a | Monoclonal Antibody to DEAD Box Polypeptide 46 (DDX46) | Monoclonal Antibody Customized Service Offer |
n/a | Polyclonal Antibody to DEAD Box Polypeptide 46 (DDX46) | Polyclonal Antibody Customized Service Offer | |
Assay Kits | n/a | CLIA Kit for DEAD Box Polypeptide 46 (DDX46) | CLIA Kit Customized Service Offer |
n/a | ELISA Kit for DEAD Box Polypeptide 46 (DDX46) | ELISA Kit Customized Service Offer |
- "Prediction of the coding sequences of unidentified human genes. XI. The complete sequences of 100 new cDNA clones from brain which code for large proteins in vitro."DNA Res. 5:277-286(1998) [PubMed] [Europe PMC] [Abstract]
- "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
- "Characterization of novel SF3b and 17S U2 snRNP proteins, including a human Prp5p homologue and an SF3b DEAD-box protein."EMBO J. 21:4978-4988(2002) [PubMed] [Europe PMC] [Abstract]
- "Global, in vivo, and site-specific phosphorylation dynamics in signaling networks."Cell 127:635-648(2006) [PubMed] [Europe PMC] [Abstract]
- "A quantitative atlas of mitotic phosphorylation."Proc. Natl. Acad. Sci. U.S.A. 105:10762-10767(2008) [PubMed] [Europe PMC] [Abstract]
- "Lys-N and trypsin cover complementary parts of the phosphoproteome in a refined SCX-based approach."Anal. Chem. 81:4493-4501(2009) [PubMed] [Europe PMC] [Abstract]
- "Quantitative phosphoproteomic analysis of T cell receptor signaling reveals system-wide modulation of protein-protein interactions."Sci. Signal. 2:RA46-RA46(2009) [PubMed] [Europe PMC] [Abstract]
- "Lysine acetylation targets protein complexes and co-regulates major cellular functions."Science 325:834-840(2009) [PubMed] [Europe PMC] [Abstract]
- "Quantitative phosphoproteomics reveals widespread full phosphorylation site occupancy during mitosis."Sci. Signal. 3:RA3-RA3(2010) [PubMed] [Europe PMC] [Abstract]
- "Initial characterization of the human central proteome."BMC Syst. Biol. 5:17-17(2011) [PubMed] [Europe PMC] [Abstract]
- "System-wide temporal characterization of the proteome and phosphoproteome of human embryonic stem cell differentiation."Sci. Signal. 4:RS3-RS3(2011) [PubMed] [Europe PMC] [Abstract]
- "An enzyme assisted RP-RPLC approach for in-depth analysis of human liver phosphoproteome."J. Proteomics 96:253-262(2014) [PubMed] [Europe PMC] [Abstract]