Oocyte Secreted Protein 2 (OOSP2)

PLAC1L, Belongs to the PLAC1 family. By using an immunoglobulin-enzyme bridge method, pregnancy-specific beta 1-glycoprotein (SP1) and placenta-specific tissue proteins were investigated in 15 cases of mucinous cystadenocarcinoma and 20 cases of serous cystadenocarcinoma. No proteins were detected in five normal ovaries. All control sections incubated with phosphate-buffered saline or normal, non-pregnant, non-immune rabbit serum in place of the first specific antiserum as well as with the antisera exhaustively absorbed with the corresponding purified antigens were negative for each protein. The detection rates are discussed in relation to the clinical stages and survival rates of the patients. PP5 and PP11, may be useful as markers in monitoring patients with ovarian adenocarcinomas as well as for their early diagnosis.