≡

DDB1 And CUL4 Associated Factor 4 (DCAF4)

[Edit]

WDR21; WDR21A; WD Repeat Domain 21

DDB1 And CUL4 Associated Factor 4 (DCAF4)
CCC S673
HGNC 20229
MGI 1921078
RGD 1306241
UniProt Q8WV16
DCAF4 encodes a WD repeat-containing protein that interacts with the Cul4-Ddb1 E3 ligase macromolecular complex. Multiple alternatively spliced transcript variants have been found for this gene.
A library of WD-repeat containing proteins has been constructed in which the repeats appear as multi-aligned sets. WD-repeat-containing proteins are those that contain 4 or more copies of the WD-repeat (tryptophan-aspartate repeat), a sequence motif approximately 31 amino acids long, that encodes a structural repeat. This repeat is described by the following profile, where x is ANY amino acid. By clicking on each high-lighted character you will obtain the distribution of amino acids found at that position of the repeat among an aligned set of WD-repeat containing proteins.

Organism species: Homo sapiens (Human)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a Recombinant DDB1 And CUL4 Associated Factor 4 (DCAF4) Recombinant Protein Customized Service Offer
Antibodies n/a Monoclonal Antibody to DDB1 And CUL4 Associated Factor 4 (DCAF4) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to DDB1 And CUL4 Associated Factor 4 (DCAF4) Polyclonal Antibody Customized Service Offer
Assay Kits n/a CLIA Kit for DDB1 And CUL4 Associated Factor 4 (DCAF4) CLIA Kit Customized Service Offer
n/a ELISA Kit for DDB1 And CUL4 Associated Factor 4 (DCAF4) ELISA Kit Customized Service Offer

Organism species: Mus musculus (Mouse)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a Recombinant DDB1 And CUL4 Associated Factor 4 (DCAF4) Recombinant Protein Customized Service Offer
Antibodies n/a Monoclonal Antibody to DDB1 And CUL4 Associated Factor 4 (DCAF4) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to DDB1 And CUL4 Associated Factor 4 (DCAF4) Polyclonal Antibody Customized Service Offer
Assay Kits n/a CLIA Kit for DDB1 And CUL4 Associated Factor 4 (DCAF4) CLIA Kit Customized Service Offer
n/a ELISA Kit for DDB1 And CUL4 Associated Factor 4 (DCAF4) ELISA Kit Customized Service Offer

Organism species: Rattus norvegicus (Rat)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a Recombinant DDB1 And CUL4 Associated Factor 4 (DCAF4) Recombinant Protein Customized Service Offer
Antibodies n/a Monoclonal Antibody to DDB1 And CUL4 Associated Factor 4 (DCAF4) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to DDB1 And CUL4 Associated Factor 4 (DCAF4) Polyclonal Antibody Customized Service Offer
Assay Kits n/a CLIA Kit for DDB1 And CUL4 Associated Factor 4 (DCAF4) CLIA Kit Customized Service Offer
n/a ELISA Kit for DDB1 And CUL4 Associated Factor 4 (DCAF4) ELISA Kit Customized Service Offer
  1. "Complete sequencing and characterization of 21,243 full-length human cDNAs." Nat. Genet. 36:40-45(2004) [PubMed] [Europe PMC] [Abstract]
  2. "The DNA sequence and analysis of human chromosome 14." Nature 421:601-607(2003) [PubMed] [Europe PMC] [Abstract]
  3. "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
  4. "The full-ORF clone resource of the German cDNA consortium."BMC Genomics 8:399-399(2007) [PubMed] [Europe PMC] [Abstract]
  5. "A family of diverse Cul4-Ddb1-interacting proteins includes Cdt2, which is required for S phase destruction of the replication factor Cdt1."Mol. Cell 23:709-721(2006) [PubMed] [Europe PMC] [Abstract]
  6. "Molecular architecture and assembly of the DDB1-CUL4A ubiquitin ligase machinery."Nature 443:590-593(2006) [PubMed] [Europe PMC] [Abstract]