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DnaJ/HSP40 Homolog Subfamily B, Member 3 (DNAJB3)

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HCG3

DnaJ/HSP40 Homolog Subfamily B, Member 3 (DNAJB3)
CCC S676
HGNC 32397
MGI 1306822
PubMed 23894433
RGD 1594215
UniProt Q8WWF6
Human encodes a DnaJ (Hsp40) homolog, subfamily B, member 3 protein. It has a single guanine nucleotide insertion, inducing an open reading frame shift, when compared with its chimpanzee ortholog. Human and chimpanzee DNAJB3 genes are predicted to encode 145 and 224 amino acid proteins, respectively. Interestingly, a comparison of human and chimpanzee DNAJB3 with macaque and mouse orthologs revealed that deletion of a thymine nucleotide near the C-terminus is common in human and chimpanzee. Macaque DNAJB3 and mouse Dnajb3 are specifically expressed in testis. It is unclear whether the chimpanzee DNAJB3 that lacks 18 C-terminal residues compared with the macaque ortholog produces a functional protein, whereas the human DNAJB3 is likely to be inactive as almost half of its residues are missing.

Organism species: Homo sapiens (Human)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a Recombinant DnaJ/HSP40 Homolog Subfamily B, Member 3 (DNAJB3) Recombinant Protein Customized Service Offer
Antibodies n/a Monoclonal Antibody to DnaJ/HSP40 Homolog Subfamily B, Member 3 (DNAJB3) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to DnaJ/HSP40 Homolog Subfamily B, Member 3 (DNAJB3) Polyclonal Antibody Customized Service Offer
Assay Kits n/a CLIA Kit for DnaJ/HSP40 Homolog Subfamily B, Member 3 (DNAJB3) CLIA Kit Customized Service Offer
n/a ELISA Kit for DnaJ/HSP40 Homolog Subfamily B, Member 3 (DNAJB3) ELISA Kit Customized Service Offer

Organism species: Mus musculus (Mouse)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a Recombinant DnaJ/HSP40 Homolog Subfamily B, Member 3 (DNAJB3) Recombinant Protein Customized Service Offer
Antibodies n/a Monoclonal Antibody to DnaJ/HSP40 Homolog Subfamily B, Member 3 (DNAJB3) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to DnaJ/HSP40 Homolog Subfamily B, Member 3 (DNAJB3) Polyclonal Antibody Customized Service Offer
Assay Kits n/a CLIA Kit for DnaJ/HSP40 Homolog Subfamily B, Member 3 (DNAJB3) CLIA Kit Customized Service Offer
n/a ELISA Kit for DnaJ/HSP40 Homolog Subfamily B, Member 3 (DNAJB3) ELISA Kit Customized Service Offer

Organism species: Rattus norvegicus (Rat)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a Recombinant DnaJ/HSP40 Homolog Subfamily B, Member 3 (DNAJB3) Recombinant Protein Customized Service Offer
Antibodies n/a Monoclonal Antibody to DnaJ/HSP40 Homolog Subfamily B, Member 3 (DNAJB3) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to DnaJ/HSP40 Homolog Subfamily B, Member 3 (DNAJB3) Polyclonal Antibody Customized Service Offer
Assay Kits n/a CLIA Kit for DnaJ/HSP40 Homolog Subfamily B, Member 3 (DNAJB3) CLIA Kit Customized Service Offer
n/a ELISA Kit for DnaJ/HSP40 Homolog Subfamily B, Member 3 (DNAJB3) ELISA Kit Customized Service Offer
  1. "Generation and annotation of the DNA sequences of human chromosomes 2 and 4." Nature 434:724-731(2005) [PubMed] [Europe PMC] [Abstract]
  2. "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
  3. "Structure of msj-1 gene in mice and humans: a possible role in the regulation of male reproduction."Gen. Comp. Endocrinol. 156:91-103(2008) [PubMed] [Europe PMC] [Abstract]
  4. "Solution structure of the DNAj domain of the human protein hcg3, a hypothetical protein tmp_locus_21."Submitted (FEB-2009) to the PDB data bank