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Histone Cluster 1, H2bk (HIST1H2BK)

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HIRIP1; H2BFT; H2BFAiii; H2B Histone Family, Member T; HIRA-Interacting Protein 1

Histone Cluster 1, H2bk (HIST1H2BK)
CCC S769
HGNC 13954
MGI 2448399
PubMed 12408966
RGD 1308088
UniProt O60814
Wiki HIST1H2BK
Histones are basic nuclear proteins that are responsible for the nucleosome structure of the chromosomal fiber in eukaryotes. Two molecules of each of the four core histones (H2A, H2B, H3, and H4) form an octamer, around which approximately 146 bp of DNA is wrapped in repeating units, called nucleosomes. The linker histone, H1, interacts with linker DNA between nucleosomes and functions in the compaction of chromatin into higher order structures.
HIST1H2BK encodes a member of the histone H2B family. This gene is found in the histone microcluster on chromosome 6p21.33. Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template.

Organism species: Homo sapiens (Human)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a Recombinant Histone Cluster 1, H2bk (HIST1H2BK) Recombinant Protein Customized Service Offer
Antibodies n/a Monoclonal Antibody to Histone Cluster 1, H2bk (HIST1H2BK) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to Histone Cluster 1, H2bk (HIST1H2BK) Polyclonal Antibody Customized Service Offer
Assay Kits n/a CLIA Kit for Histone Cluster 1, H2bk (HIST1H2BK) CLIA Kit Customized Service Offer
n/a ELISA Kit for Histone Cluster 1, H2bk (HIST1H2BK) ELISA Kit Customized Service Offer

Organism species: Mus musculus (Mouse)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a Recombinant Histone Cluster 1, H2bk (HIST1H2BK) Recombinant Protein Customized Service Offer
Antibodies n/a Monoclonal Antibody to Histone Cluster 1, H2bk (HIST1H2BK) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to Histone Cluster 1, H2bk (HIST1H2BK) Polyclonal Antibody Customized Service Offer
Assay Kits n/a CLIA Kit for Histone Cluster 1, H2bk (HIST1H2BK) CLIA Kit Customized Service Offer
n/a ELISA Kit for Histone Cluster 1, H2bk (HIST1H2BK) ELISA Kit Customized Service Offer

Organism species: Rattus norvegicus (Rat)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a Recombinant Histone Cluster 1, H2bk (HIST1H2BK) Recombinant Protein Customized Service Offer
Antibodies n/a Monoclonal Antibody to Histone Cluster 1, H2bk (HIST1H2BK) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to Histone Cluster 1, H2bk (HIST1H2BK) Polyclonal Antibody Customized Service Offer
Assay Kits n/a CLIA Kit for Histone Cluster 1, H2bk (HIST1H2BK) CLIA Kit Customized Service Offer
n/a ELISA Kit for Histone Cluster 1, H2bk (HIST1H2BK) ELISA Kit Customized Service Offer
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  12. "Monoubiquitination of human histone H2B: the factors involved and their roles in HOX gene regulation."Mol. Cell 20:601-611(2005) [PubMed] [Europe PMC] [Abstract]
  13. "Inhibition of core histones acetylation by carcinogenic nickel(II)."Mol. Cell. Biochem. 279:133-139(2005) [PubMed] [Europe PMC] [Abstract]
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  15. "The RING finger protein MSL2 in the MOF complex is an E3 ubiquitin ligase for H2B K34 and is involved in crosstalk with H3 K4 and K79 methylation."Mol. Cell 43:132-144(2011) [PubMed] [Europe PMC] [Abstract]
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  19. "USP49 deubiquitinates histone H2B and regulates cotranscriptional pre-mRNA splicing."Genes Dev. 27:1581-1595(2013) [PubMed] [Europe PMC] [Abstract]