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H3 Histone Family 3C (H3F3C)

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H3 Histone Family 3C (H3F3C)
CCC S770
HGNC 33164
UniProt Q6NXT2
H3F3C belongs to the histone H3 family. The nucleosome is a histone octamer containing two molecules each of H2A, H2B, H3 and H4 assembled in one H3-H4 heterotetramer and two H2A-H2B heterodimers. The octamer wraps approximately 147 bp of DNA.
Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling.

Organism species: Homo sapiens (Human)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a Recombinant H3 Histone Family 3C (H3F3C) Recombinant Protein Customized Service Offer
Antibodies n/a Monoclonal Antibody to H3 Histone Family 3C (H3F3C) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to H3 Histone Family 3C (H3F3C) Polyclonal Antibody Customized Service Offer
Assay Kits n/a CLIA Kit for H3 Histone Family 3C (H3F3C) CLIA Kit Customized Service Offer
n/a ELISA Kit for H3 Histone Family 3C (H3F3C) ELISA Kit Customized Service Offer
  1. "H3.5 is a novel hominid-specific histone H3 variant that is specifically expressed in the seminiferous tubules of human testes."Chromosoma 120:275-285(2011) [PubMed] [Europe PMC] [Abstract]
  2. "The finished DNA sequence of human chromosome 12." Nature 440:346-351(2006) [PubMed] [Europe PMC] [Abstract]
  3. "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
  4. "Quantitative interaction proteomics and genome-wide profiling of epigenetic histone marks and their readers."Cell 142:967-980(2010) [PubMed] [Europe PMC] [Abstract]