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Histone Cluster 2, H2bd (HIST2H2BD)

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H2BFO; H2B/s; H2B/o; H2B Histone Family, Member O

Histone Cluster 2, H2bd (HIST2H2BD)
CCC S775
HGNC 20517
UniProt Q6DRA6
HIST2H2BD, Belongs to the histone H2B family. The nucleosome is a histone octamer containing two molecules each of H2A, H2B, H3 and H4 assembled in one H3-H4 heterotetramer and two H2A-H2B heterodimers. The octamer wraps approximately 147 bp of DNA.
Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling. The mouse orthologous protein seems not to exist.

Organism species: Homo sapiens (Human)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a Recombinant Histone Cluster 2, H2bd (HIST2H2BD) Recombinant Protein Customized Service Offer
Antibodies n/a Monoclonal Antibody to Histone Cluster 2, H2bd (HIST2H2BD) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to Histone Cluster 2, H2bd (HIST2H2BD) Polyclonal Antibody Customized Service Offer
Assay Kits n/a CLIA Kit for Histone Cluster 2, H2bd (HIST2H2BD) CLIA Kit Customized Service Offer
n/a ELISA Kit for Histone Cluster 2, H2bd (HIST2H2BD) ELISA Kit Customized Service Offer
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