Solute Carrier Family 22, Member 19 (SLC22A19)

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OAT5; Slc22a9; Organic Anion Transporter 5

Solute Carrier Family 22, Member 19 (SLC22A19)
Oat5 (Slc22a19), has been reported to transport a naturally occurring mycotoxin, ochratoxin A (OTA). The rOat5-mediated E(1)S transport was strongly inhibited by four-carbon (C4) dicarboxylate succinate and longer dicarboxylates (C7-C9). rOat5 interacted with chemically heterogenous anionic compounds. The rOat5-mediated E(1)S transport was inhibited by several sulfate conjugates, such as 4-methylumbelliferyl sulfate and beta-estradiol sulfate, but not by glucuronide conjugates. rOat5 was localized at the apical membrane of renal proximal tubules in the corticomedullary region. rOat5 mRNA was expressed in the late segments (S(2) and S(3)) of proximal tubules. rOat5 is renal organic anion/dicarboxylates exchanger and, under physiological conditions, may function as an apical reabsorptive pathway for organic anions in proximal tubules driven by an outward gradient of dicarboxylates.

Organism species: Mus musculus (Mouse)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a Recombinant Solute Carrier Family 22, Member 19 (SLC22A19) Recombinant Protein Customized Service Offer
Antibodies n/a Monoclonal Antibody to Solute Carrier Family 22, Member 19 (SLC22A19) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to Solute Carrier Family 22, Member 19 (SLC22A19) Polyclonal Antibody Customized Service Offer
Assay Kits n/a CLIA Kit for Solute Carrier Family 22, Member 19 (SLC22A19) CLIA Kit Customized Service Offer
n/a ELISA Kit for Solute Carrier Family 22, Member 19 (SLC22A19) ELISA Kit Customized Service Offer

Organism species: Rattus norvegicus (Rat)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a Recombinant Solute Carrier Family 22, Member 19 (SLC22A19) Recombinant Protein Customized Service Offer
Antibodies n/a Monoclonal Antibody to Solute Carrier Family 22, Member 19 (SLC22A19) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to Solute Carrier Family 22, Member 19 (SLC22A19) Polyclonal Antibody Customized Service Offer
Assay Kits n/a CLIA Kit for Solute Carrier Family 22, Member 19 (SLC22A19) CLIA Kit Customized Service Offer
n/a ELISA Kit for Solute Carrier Family 22, Member 19 (SLC22A19) ELISA Kit Customized Service Offer
  1. "A comparison of whole-genome shotgun-derived mouse chromosome 16 and the human genome." Science 296:1661-1671(2002) [PubMed] [Europe PMC] [Abstract].
  2. "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)." Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]. : .