Solute Carrier Organic Anion Transporter Family, Member 1A5 (SLCO1A5)

SLCO1A5, Belongs to the organo anion transporter (TC 2.A.60) family.Contains 1 Kazal-like domain. Highly expressed in the kidney and moderately abundant in the retina. Mediates the Na⁺-independent transport of organic anions such as taurocholate and thyroid hormones. The SLC group of membrane transport proteins include over 300 members organized into 47 families. The SLC gene nomenclature system was originally proposed by the Human Genome Organization and is the basis for the official HUGO names of the genes that encode these transporters. A more general transmembrane transporter classification can be found in TCDB database. Solutes that are transported by the various SLC group members are extraordinarily diverse and include both charged and uncharged organic molecules as well as inorganic ions.