Flap Structure Specific Endonuclease 1 (FEN1)is a nuclear enzyme involved in DNA metabolism, such as replication, repair, and recombination.
The comparative genomic organization of the chicken, mouse, and human FEN1 genes as well as the comparative organization of a small gene (C11orf10) located immediately upstream of the FEN1 gene in reverse orientation. Immunostaining revealed that the C11orf10 protein, unlike FEN-1, is located in the cytoplasm, suggesting that these two proteins do not form a physical complex. Importantly, in the human genome, the two mRNAs are overlapping (14 bp) in their 5' ends. Thus, the FEN1/C11orf10 locus is a new example of two overlapping, divergent transcription units in the human genome.
Organism species: Homo sapiens (Human)
CATALOG NO. | PRODUCT NAME | APPLICATIONS | |
Proteins | n/a | Recombinant Transmembrane Protein 258 (TMEM258) | Recombinant Protein Customized Service Offer |
Antibodies | n/a | Monoclonal Antibody to Transmembrane Protein 258 (TMEM258) | Monoclonal Antibody Customized Service Offer |
n/a | Polyclonal Antibody to Transmembrane Protein 258 (TMEM258) | Polyclonal Antibody Customized Service Offer | |
Assay Kits | n/a | CLIA Kit for Transmembrane Protein 258 (TMEM258) | CLIA Kit Customized Service Offer |
n/a | ELISA Kit for Transmembrane Protein 258 (TMEM258) | ELISA Kit Customized Service Offer |
Organism species: Mus musculus (Mouse)
CATALOG NO. | PRODUCT NAME | APPLICATIONS | |
Proteins | n/a | Recombinant Transmembrane Protein 258 (TMEM258) | Recombinant Protein Customized Service Offer |
Antibodies | n/a | Monoclonal Antibody to Transmembrane Protein 258 (TMEM258) | Monoclonal Antibody Customized Service Offer |
n/a | Polyclonal Antibody to Transmembrane Protein 258 (TMEM258) | Polyclonal Antibody Customized Service Offer | |
Assay Kits | n/a | CLIA Kit for Transmembrane Protein 258 (TMEM258) | CLIA Kit Customized Service Offer |
n/a | ELISA Kit for Transmembrane Protein 258 (TMEM258) | ELISA Kit Customized Service Offer |
Organism species: Rattus norvegicus (Rat)
CATALOG NO. | PRODUCT NAME | APPLICATIONS | |
Proteins | n/a | Recombinant Transmembrane Protein 258 (TMEM258) | Recombinant Protein Customized Service Offer |
Antibodies | n/a | Monoclonal Antibody to Transmembrane Protein 258 (TMEM258) | Monoclonal Antibody Customized Service Offer |
n/a | Polyclonal Antibody to Transmembrane Protein 258 (TMEM258) | Polyclonal Antibody Customized Service Offer | |
Assay Kits | n/a | CLIA Kit for Transmembrane Protein 258 (TMEM258) | CLIA Kit Customized Service Offer |
n/a | ELISA Kit for Transmembrane Protein 258 (TMEM258) | ELISA Kit Customized Service Offer |
- "Cloning and functional analysis of cDNAs with open reading frames for 300 previously undefined genes expressed in CD34+ hematopoietic stem/progenitor cells." Genome Res. 10:1546-1560(2000) [PubMed] [Europe PMC] [Abstract]
- "Complete sequencing and characterization of 21,243 full-length human cDNAs." Nat. Genet. 36:40-45(2004) [PubMed] [Europe PMC] [Abstract]
- "Human chromosome 11 DNA sequence and analysis including novel gene identification." Nature 440:497-500(2006) [PubMed] [Europe PMC] [Abstract]
- "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
- "Exploring proteomes and analyzing protein processing by mass spectrometric identification of sorted N-terminal peptides."Nat. Biotechnol. 21:566-569(2003) [PubMed] [Europe PMC] [Abstract]
- "Lys-N and trypsin cover complementary parts of the phosphoproteome in a refined SCX-based approach."Anal. Chem. 81:4493-4501(2009) [PubMed] [Europe PMC] [Abstract]
- "Comparative large-scale characterisation of plant vs. mammal proteins reveals similar and idiosyncratic N-alpha acetylation features."Mol. Cell. Proteomics 11:M111.015131-M111.015131(2012) [PubMed] [Europe PMC] [Abstract]
- "N-terminal acetylome analyses and functional insights of the N-terminal acetyltransferase NatB."Proc. Natl. Acad. Sci. U.S.A. 109:12449-12454(2012) [PubMed] [Europe PMC] [Abstract]