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DMRTC1 (DMRT-like family C1) is a 182 amino acid nuclear protein that exists as three alternatively spliced isoforms and belongs to the DMRT family. Involved in sexual development, DMRTC1 is expressed in Sertoli cells in male testis but, unlike other DMRT family members, it does not contain a DM DNA-binding domain. Highly expressed in ovary and testis. Detected in brain and in many other tissues. The gene encoding DMRTC1 maps to the human X chromosome, which consists of about 153 million base pairs and nearly 1,000 genes. The combination of an X and Y chromosome lead to normal male development while two copies of X lead to normal female development. There are a number of conditions related to an unsual number and combination of sex chromosomes being inherited, including Klinefelter’s syndrome, Turner’s syndrome, and Triple X syndrome.
Organism species: Homo sapiens (Human)
| CATALOG NO. | PRODUCT NAME | APPLICATIONS | |
| Proteins | n/a | Recombinant DMRT Like Family C1 (DMRTC1) | Recombinant Protein Customized Service Offer |
| Antibodies | n/a | Monoclonal Antibody to DMRT Like Family C1 (DMRTC1) | Monoclonal Antibody Customized Service Offer |
| n/a | Polyclonal Antibody to DMRT Like Family C1 (DMRTC1) | Polyclonal Antibody Customized Service Offer | |
| Assay Kits | n/a | CLIA Kit for DMRT Like Family C1 (DMRTC1) | CLIA Kit Customized Service Offer |
| n/a | ELISA Kit for DMRT Like Family C1 (DMRTC1) | ELISA Kit Customized Service Offer |
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- "Novel paralogy relations among human chromosomes support a link between the phylogeny of doublesex-related genes and the evolution of sex determination."Genomics 79:333-343(2002) [PubMed] [Europe PMC] [Abstract]