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DDRGK Domain Containing Protein 1 (DDRGK1)

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C20orf116; UFBP1; UFM1-binding and PCI domain-containing protein 1

DDRGK Domain Containing Protein 1 (DDRGK1)
CCC T357
HGNC 16110
MGI 1924256
PubMed 21659334
RGD 1309979
UniProt Q96HY6
DDRGK1is a 314 amino acid secreted protein. DDRGK1 contains one PCI domain and is expressed as two isoforms produced by alternative splicing. The gene that encodes DDRGK1 maps to human chromosome 20, which represents about 2% of human DNA and consists of approximately 63 million bases and 600 genes. Chromosome 20 contains a region with numerous genes expressed in the epididymis, which are thought to be important for seminal production. The PRNP gene encoding the prion protein associated with spongiform encephalopathies, like Creutzfeldt-Jakob disease, is found on chromosome 20. Amyotrophic lateral sclerosis, spinal muscular atrophy, ring chromosome 20 epilepsy syndrome and Alagille syndrome are also associated with chromosome 20.

Organism species: Homo sapiens (Human)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a Recombinant DDRGK Domain Containing Protein 1 (DDRGK1) Recombinant Protein Customized Service Offer
Antibodies n/a Monoclonal Antibody to DDRGK Domain Containing Protein 1 (DDRGK1) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to DDRGK Domain Containing Protein 1 (DDRGK1) Polyclonal Antibody Customized Service Offer
Assay Kits n/a CLIA Kit for DDRGK Domain Containing Protein 1 (DDRGK1) CLIA Kit Customized Service Offer
n/a ELISA Kit for DDRGK Domain Containing Protein 1 (DDRGK1) ELISA Kit Customized Service Offer

Organism species: Mus musculus (Mouse)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a Recombinant DDRGK Domain Containing Protein 1 (DDRGK1) Recombinant Protein Customized Service Offer
Antibodies n/a Monoclonal Antibody to DDRGK Domain Containing Protein 1 (DDRGK1) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to DDRGK Domain Containing Protein 1 (DDRGK1) Polyclonal Antibody Customized Service Offer
Assay Kits n/a CLIA Kit for DDRGK Domain Containing Protein 1 (DDRGK1) CLIA Kit Customized Service Offer
n/a ELISA Kit for DDRGK Domain Containing Protein 1 (DDRGK1) ELISA Kit Customized Service Offer

Organism species: Rattus norvegicus (Rat)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a Recombinant DDRGK Domain Containing Protein 1 (DDRGK1) Recombinant Protein Customized Service Offer
Antibodies n/a Monoclonal Antibody to DDRGK Domain Containing Protein 1 (DDRGK1) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to DDRGK Domain Containing Protein 1 (DDRGK1) Polyclonal Antibody Customized Service Offer
Assay Kits n/a CLIA Kit for DDRGK Domain Containing Protein 1 (DDRGK1) CLIA Kit Customized Service Offer
n/a ELISA Kit for DDRGK Domain Containing Protein 1 (DDRGK1) ELISA Kit Customized Service Offer
  1. "The secreted protein discovery initiative (SPDI), a large-scale effort to identify novel human secreted and transmembrane proteins: a bioinformatics assessment." Genome Res. 13:2265-2270(2003) [PubMed] [Europe PMC] [Abstract]
  2. "The DNA sequence and comparative analysis of human chromosome 20." Nature 414:865-871(2001) [PubMed] [Europe PMC] [Abstract]
  3. "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
  4. "A novel type of E3 ligase for the Ufm1 conjugation system."J. Biol. Chem. 285:5417-5427(2010) [PubMed] [Europe PMC] [Abstract]
  5. "A novel C53/LZAP-interacting protein regulates stability of C53/LZAP and DDRGK domain-containing Protein 1 (DDRGK1) and modulates NF-kappaB signaling."J. Biol. Chem. 285:15126-15136(2010) [PubMed] [Europe PMC] [Abstract]
  6. "Initial characterization of the human central proteome."BMC Syst. Biol. 5:17-17(2011) [PubMed] [Europe PMC] [Abstract]
  7. "DDRGK1 regulates NF-kappaB activity by modulating IkappaBalpha stability."PLoS ONE 8:E64231-E64231(2013) [PubMed] [Europe PMC] [Abstract]
  8. "An enzyme assisted RP-RPLC approach for in-depth analysis of human liver phosphoproteome."J. Proteomics 96:253-262(2014) [PubMed] [Europe PMC] [Abstract]
  9. "Modification of ASC1 by UFM1 is crucial for ERalpha transactivation and breast cancer development."Mol. Cell 56:261-274(2014) [PubMed] [Europe PMC] [Abstract]