R3H Domain Containing Like Protein (R3HDML)
[Edit]Peptidase inhibitor R3HDML; Cysteine-rich secretory protein R3HDML;
A conserved sequence motif, the R3H domain has been identified in over 100 proteins and is suggested to be involved in polynucleotide-binding, including DNA, RNA and single-stranded DNA. R3HDML (R3H domain containing-like) is a 253 amino acid cysteine-rich secretory protein belonging to the CRISP family. Considered a putative serine protease inhibitor, is encoded by a gene located on human chromosome 20, which contains nearly 63 million bases and encodes over 600 genes, some of which are associated with Creutzfeldt-Jakob disease, amyotrophic lateral sclerosis, spinal muscular atrophy, ring chromosome 20 epilepsy syndrome and Alagille syndrome. Additionally, chromosome 20 contains a region with numerous genes that are thought to be important for seminal production and may be potential targets for male contraception.
Organism species: Homo sapiens (Human)
CATALOG NO. | PRODUCT NAME | APPLICATIONS | |
Proteins | n/a | Recombinant R3H Domain Containing Like Protein (R3HDML) | Recombinant Protein Customized Service Offer |
Antibodies | n/a | Monoclonal Antibody to R3H Domain Containing Like Protein (R3HDML) | Monoclonal Antibody Customized Service Offer |
n/a | Polyclonal Antibody to R3H Domain Containing Like Protein (R3HDML) | Polyclonal Antibody Customized Service Offer | |
Assay Kits | n/a | CLIA Kit for R3H Domain Containing Like Protein (R3HDML) | CLIA Kit Customized Service Offer |
n/a | ELISA Kit for R3H Domain Containing Like Protein (R3HDML) | ELISA Kit Customized Service Offer |
Organism species: Mus musculus (Mouse)
CATALOG NO. | PRODUCT NAME | APPLICATIONS | |
Proteins | n/a | Recombinant R3H Domain Containing Like Protein (R3HDML) | Recombinant Protein Customized Service Offer |
Antibodies | n/a | Monoclonal Antibody to R3H Domain Containing Like Protein (R3HDML) | Monoclonal Antibody Customized Service Offer |
n/a | Polyclonal Antibody to R3H Domain Containing Like Protein (R3HDML) | Polyclonal Antibody Customized Service Offer | |
Assay Kits | n/a | CLIA Kit for R3H Domain Containing Like Protein (R3HDML) | CLIA Kit Customized Service Offer |
n/a | ELISA Kit for R3H Domain Containing Like Protein (R3HDML) | ELISA Kit Customized Service Offer |
- "The DNA sequence and comparative analysis of human chromosome 20." Nature 414:865-871(2001) [PubMed] [Europe PMC] [Abstract]
- "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]