ZNF280A was predicted both by automated computational analysis and by similarity to a Drosophila gene and to predicted genes in other species (sheep, chimp, dog, cow). The predicted protein of this gene is similar to Drosophila suppressor of hairy wing protein, a leucine zipper protein which represses the function of transcriptional enhancers of the gypsy retrotransposon.
The majority of zinc-finger proteins contain a krueppel-type DNA binding domain and a KRAB domain, which is thought to interact with KAP1, thereby recruiting histone modifying proteins. SUHW1 is a 542 amino acid protein that contains four C2H2-type zinc fingers. Localized to the nucleus, SUHW1 is thought to function as a transcription factor that may mediate transcriptional regulation events.
Organism species: Homo sapiens (Human)
CATALOG NO. | PRODUCT NAME | APPLICATIONS | |
Proteins | n/a | Recombinant Zinc Finger Protein 280A (ZNF280A) | Recombinant Protein Customized Service Offer |
Antibodies | n/a | Monoclonal Antibody to Zinc Finger Protein 280A (ZNF280A) | Monoclonal Antibody Customized Service Offer |
n/a | Polyclonal Antibody to Zinc Finger Protein 280A (ZNF280A) | Polyclonal Antibody Customized Service Offer | |
Assay Kits | n/a | CLIA Kit for Zinc Finger Protein 280A (ZNF280A) | CLIA Kit Customized Service Offer |
n/a | ELISA Kit for Zinc Finger Protein 280A (ZNF280A) | ELISA Kit Customized Service Offer |
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