≡

Polypeptide-N-Acetylgalactosaminyltransferase 11 (GALNT11)

[Edit]

GalNAc-T11; Polypeptide GalNAc transferase 11; UDP-GalNAc:polypeptide N-acetylgalactosaminyltransferase 11

Polypeptide-N-Acetylgalactosaminyltransferase 11 (GALNT11)
CCC T485
HGNC 19875
MGI 2444392
PubMed 24076351
RGD 735097
UniProt Q8NCW6
Wiki GALNT11
The completed fruit fly genome was found to contain up to 15 putative UDP-N-acetyl-alpha-d-galactosamine:polypeptide N-acetylgalactosaminyltransferase (GalNAc-transferase) genes. Distinctive functional properties of Drosophila and human GalNAc-transferase isoforms were exhibited by evolutionarily conserved members of two subfamilies (dGalNAc-T1 (l(2)35Aa) and GalNAc-T11; dGalNAc-T2 (CG6394) and GalNAc-T7). dGalNAc-T1 and novel human GalNAc-T11 were shown to encode functional GalNAc-transferases with the same polypeptide acceptor substrate specificity, and dGalNAc-T2 was shown to encode a GalNAc-transferase with similar GalNAc glycopeptide substrate specificity as GalNAc-T7. Previous data suggested that the putative GalNAc-transferase encoded by l(2)35Aa had a lethal phenotype.

Organism species: Homo sapiens (Human)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a Recombinant Polypeptide-N-Acetylgalactosaminyltransferase 11 (GALNT11) Recombinant Protein Customized Service Offer
Antibodies n/a Monoclonal Antibody to Polypeptide-N-Acetylgalactosaminyltransferase 11 (GALNT11) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to Polypeptide-N-Acetylgalactosaminyltransferase 11 (GALNT11) Polyclonal Antibody Customized Service Offer
Assay Kits n/a CLIA Kit for Polypeptide-N-Acetylgalactosaminyltransferase 11 (GALNT11) CLIA Kit Customized Service Offer
n/a ELISA Kit for Polypeptide-N-Acetylgalactosaminyltransferase 11 (GALNT11) ELISA Kit Customized Service Offer

Organism species: Mus musculus (Mouse)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a Recombinant Polypeptide-N-Acetylgalactosaminyltransferase 11 (GALNT11) Recombinant Protein Customized Service Offer
Antibodies n/a Monoclonal Antibody to Polypeptide-N-Acetylgalactosaminyltransferase 11 (GALNT11) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to Polypeptide-N-Acetylgalactosaminyltransferase 11 (GALNT11) Polyclonal Antibody Customized Service Offer
Assay Kits n/a CLIA Kit for Polypeptide-N-Acetylgalactosaminyltransferase 11 (GALNT11) CLIA Kit Customized Service Offer
n/a ELISA Kit for Polypeptide-N-Acetylgalactosaminyltransferase 11 (GALNT11) ELISA Kit Customized Service Offer

Organism species: Rattus norvegicus (Rat)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a Recombinant Polypeptide-N-Acetylgalactosaminyltransferase 11 (GALNT11) Recombinant Protein Customized Service Offer
Antibodies n/a Monoclonal Antibody to Polypeptide-N-Acetylgalactosaminyltransferase 11 (GALNT11) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to Polypeptide-N-Acetylgalactosaminyltransferase 11 (GALNT11) Polyclonal Antibody Customized Service Offer
Assay Kits n/a CLIA Kit for Polypeptide-N-Acetylgalactosaminyltransferase 11 (GALNT11) CLIA Kit Customized Service Offer
n/a ELISA Kit for Polypeptide-N-Acetylgalactosaminyltransferase 11 (GALNT11) ELISA Kit Customized Service Offer
  1. "Functional conservation of subfamilies of putative UDP-N-acetylgalactosamine:polypeptide N-acetylgalactosaminyltransferases in Drosophila, Caenorhabditis elegans, and mammals. One subfamily composed of l(2)35Aa is essential in Drosophila."J. Biol. Chem. 277:22623-22638(2002) [PubMed] [Europe PMC] [Abstract]
  2. "Complete sequencing and characterization of 21,243 full-length human cDNAs." Nat. Genet. 36:40-45(2004) [PubMed] [Europe PMC] [Abstract]
  3. "The DNA sequence of human chromosome 7." Nature 424:157-164(2003) [PubMed] [Europe PMC] [Abstract]
  4. "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
  5. "Rare copy number variations in congenital heart disease patients identify unique genes in left-right patterning."Proc. Natl. Acad. Sci. U.S.A. 108:2915-2920(2011) [PubMed] [Europe PMC] [Abstract]
  6. "The heterotaxy gene GALNT11 glycosylates Notch to orchestrate cilia type and laterality."Nature 504:456-459(2013) [PubMed] [Europe PMC] [Abstract]
  7. "A Japanese-specific allele in the GALNT11 gene."Leg. Med. 12:208-211(2010) [PubMed] [Europe PMC] [Abstract]