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SR Related CTD Associated Factor 8 (SCAF8)

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RBM16; CCAP7; RNA Binding Motif Protein 16; CDC5L complex-associated protein 7; RNA-binding motif protein 16

SR Related CTD Associated Factor 8 (SCAF8)
CCC T569
HGNC 20959
MGI 1925212
PubMed 18550522
UniProt Q9UPN6
Concomitant with RNA polymerase II (Pol II) transcription, RNA maturation factors are recruited to the carboxyl-terminal domain (CTD) of Pol II, whose phosphorylation state changes during a transcription cycle. CTD phosphorylation triggers recruitment of functionally different factors involved in RNA processing and transcription termination; most of these factors harbor a conserved CTD interacting domain (CID). Orchestration of factor recruitment is believed to be conducted by CID recognition of distinct phosphorylated forms of the CTD.
SCAF8 interacts weakly with the unphosphorylated CTD of Pol II. Upon phosphorylation, affinity for the CTD is increased; however, SCAF8 is promiscuous to the phosphorylation pattern on the CTD.

Organism species: Homo sapiens (Human)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a Recombinant SR Related CTD Associated Factor 8 (SCAF8) Recombinant Protein Customized Service Offer
Antibodies n/a Monoclonal Antibody to SR Related CTD Associated Factor 8 (SCAF8) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to SR Related CTD Associated Factor 8 (SCAF8) Polyclonal Antibody Customized Service Offer
Assay Kits n/a CLIA Kit for SR Related CTD Associated Factor 8 (SCAF8) CLIA Kit Customized Service Offer
n/a ELISA Kit for SR Related CTD Associated Factor 8 (SCAF8) ELISA Kit Customized Service Offer

Organism species: Mus musculus (Mouse)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a Recombinant SR Related CTD Associated Factor 8 (SCAF8) Recombinant Protein Customized Service Offer
Antibodies n/a Monoclonal Antibody to SR Related CTD Associated Factor 8 (SCAF8) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to SR Related CTD Associated Factor 8 (SCAF8) Polyclonal Antibody Customized Service Offer
Assay Kits n/a CLIA Kit for SR Related CTD Associated Factor 8 (SCAF8) CLIA Kit Customized Service Offer
n/a ELISA Kit for SR Related CTD Associated Factor 8 (SCAF8) ELISA Kit Customized Service Offer
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