Keratin Associated Protein 5-4 (KRTAP5-4)

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Ultrahigh sulfur keratin-associated protein 5.4

Keratin Associated Protein 5-4 (KRTAP5-4)
is a member of the keratin-associated protein (KAP) family. The KAP proteins form a matrix of keratin intermediate filaments which contribute to the structure of hair fibers. KAP family members appear to have unique, family-specific amino- and carboxyl-terminal regions and are subdivided into three multi-gene families according to amino acid composition: the high sulfur, the ultrahigh sulfur, and the high tyrosine/glycine KAPs. This protein is a member of the ultrahigh sulfur KAP family and the gene is localized to a cluster of KAPs at 17q12-q21. In the hair cortex, hair keratin intermediate filaments are embedded in an interfilamentous matrix, consisting of hair keratin-associated proteins (KRTAP), which are essential for the formation of a rigid and resistant hair shaft through their extensive disulfide bond cross-linking with abundant cysteine residues of hair keratins.

Organism species: Homo sapiens (Human)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a Recombinant Keratin Associated Protein 5-4 (KRTAP5-4) Recombinant Protein Customized Service Offer
Antibodies n/a Monoclonal Antibody to Keratin Associated Protein 5-4 (KRTAP5-4) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to Keratin Associated Protein 5-4 (KRTAP5-4) Polyclonal Antibody Customized Service Offer
Assay Kits n/a CLIA Kit for Keratin Associated Protein 5-4 (KRTAP5-4) CLIA Kit Customized Service Offer
n/a ELISA Kit for Keratin Associated Protein 5-4 (KRTAP5-4) ELISA Kit Customized Service Offer

Organism species: Rattus norvegicus (Rat)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a Recombinant Keratin Associated Protein 5-4 (KRTAP5-4) Recombinant Protein Customized Service Offer
Antibodies n/a Monoclonal Antibody to Keratin Associated Protein 5-4 (KRTAP5-4) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to Keratin Associated Protein 5-4 (KRTAP5-4) Polyclonal Antibody Customized Service Offer
Assay Kits n/a CLIA Kit for Keratin Associated Protein 5-4 (KRTAP5-4) CLIA Kit Customized Service Offer
n/a ELISA Kit for Keratin Associated Protein 5-4 (KRTAP5-4) ELISA Kit Customized Service Offer
  1. "Identification of two novel clusters of ultrahigh-sulfur keratin-associated protein genes on human chromosome 11."Biochem. Biophys. Res. Commun. 318:655-664(2004) [PubMed] [Europe PMC] [Abstract]