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Low Density Lipoprotein Receptor Related Protein 5 Like Protein (LRP5L)

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Low Density Lipoprotein Receptor Related Protein 5 Like Protein (LRP5L)
CCC T667
HGNC 25323
UniProt A4QPB2
Members of the LDL receptor gene family, including LDLR, LRPs, megalin, VLDLR and ApoER2, are characterized by a cluster of cysteine-rich class A repeats, epidermal growth factor (EGF)-like repeats, YWTD repeats and an O-linked sugar domain. Of the known family members, LRP5 is most closely related to LRP1. However, LRP5 has a unique organization of EGF and LDLR repeats compared to other LDLR family members and likely represents a new category in this family. LRP is expressed in rat tibia, specifically in areas of the bone that are involved in remodeling. LRP5 is a Wnt coreceptor that binds to Axin and regulates the canonical Wnt signaling pathway. LRP5 affects bone mass accrual during growth. Mutations in LRP5 cause the autosomal recessive disorder osteoporosispseudoglioma syndrome (OPPG). is a related protein that exists as two isoforms produced by alternative splicing.

Organism species: Homo sapiens (Human)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins RPT667Hu01 Recombinant Low Density Lipoprotein Receptor Related Protein 5 Like Protein (LRP5L) Positive Control; Immunogen; SDS-PAGE; WB.
Antibodies PAT667Hu01 Polyclonal Antibody to Low Density Lipoprotein Receptor Related Protein 5 Like Protein (LRP5L) WB; IHC; ICC; IP.
Assay Kits n/a CLIA Kit for Low Density Lipoprotein Receptor Related Protein 5 Like Protein (LRP5L) CLIA Kit Customized Service Offer
n/a ELISA Kit for Low Density Lipoprotein Receptor Related Protein 5 Like Protein (LRP5L) ELISA Kit Customized Service Offer
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