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Transmembrane Protein 184C (TMEM184C)

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TMEM34

Transmembrane Protein 184C (TMEM184C)
CCC T673
HGNC 25587
MGI 2384562
PubMed 21636067
RGD 727852
UniProt Q9NVA4
Ansaplastic thyroid cancer (ATC) is one of the most lethal malignancies, but the carcinogenic mechanism of ATC has not been clarified.A cDNA microarray analysis and identified transmembrane protein 34 (TMEM34) that down-regulated in anaplastic thyroid cancer cell lines (ACL)s as compared to normal thyroid tissues.
Expression of TMEM34 was down-regulated in all 11 ACLs, as compared to either normal thyroid tissues or cell lines derived from papillary or follicular thyroid cancers. TMEM34 was expressed ubiquitously in normal human tissues tested. Transfection of TMEM34 into KTA2 cells led to inhibition of cell growth.TMEM34 might be a tumor suppressor gene, associated with the development of ATC from DTC.

Organism species: Homo sapiens (Human)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a Recombinant Transmembrane Protein 184C (TMEM184C) Recombinant Protein Customized Service Offer
Antibodies n/a Monoclonal Antibody to Transmembrane Protein 184C (TMEM184C) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to Transmembrane Protein 184C (TMEM184C) Polyclonal Antibody Customized Service Offer
Assay Kits n/a CLIA Kit for Transmembrane Protein 184C (TMEM184C) CLIA Kit Customized Service Offer
n/a ELISA Kit for Transmembrane Protein 184C (TMEM184C) ELISA Kit Customized Service Offer

Organism species: Mus musculus (Mouse)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a Recombinant Transmembrane Protein 184C (TMEM184C) Recombinant Protein Customized Service Offer
Antibodies n/a Monoclonal Antibody to Transmembrane Protein 184C (TMEM184C) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to Transmembrane Protein 184C (TMEM184C) Polyclonal Antibody Customized Service Offer
Assay Kits n/a CLIA Kit for Transmembrane Protein 184C (TMEM184C) CLIA Kit Customized Service Offer
n/a ELISA Kit for Transmembrane Protein 184C (TMEM184C) ELISA Kit Customized Service Offer

Organism species: Rattus norvegicus (Rat)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a Recombinant Transmembrane Protein 184C (TMEM184C) Recombinant Protein Customized Service Offer
Antibodies n/a Monoclonal Antibody to Transmembrane Protein 184C (TMEM184C) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to Transmembrane Protein 184C (TMEM184C) Polyclonal Antibody Customized Service Offer
Assay Kits n/a CLIA Kit for Transmembrane Protein 184C (TMEM184C) CLIA Kit Customized Service Offer
n/a ELISA Kit for Transmembrane Protein 184C (TMEM184C) ELISA Kit Customized Service Offer
  1. "Complete sequencing and characterization of 21,243 full-length human cDNAs." Nat. Genet. 36:40-45(2004) [PubMed] [Europe PMC] [Abstract]
  2. "Generation and annotation of the DNA sequences of human chromosomes 2 and 4." Nature 434:724-731(2005) [PubMed] [Europe PMC] [Abstract]
  3. "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
  4. "Gene expression profiling in human fetal liver and identification of tissue- and developmental-stage-specific genes through compiled expression profiles and efficient cloning of full-length cDNAs."Genome Res. 11:1392-1403(2001) [PubMed] [Europe PMC] [Abstract]
  5. "Down-regulation of an inhibitor of cell growth, transmembrane protein 34 (TMEM34), in anaplastic thyroid cancer."J. Cancer Res. Clin. Oncol. 133:213-218(2007) [PubMed] [Europe PMC] [Abstract]