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Hedgehog Interacting Protein Like Protein 2 (HHIPL2)

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HHIP3

Hedgehog Interacting Protein Like Protein 2 (HHIPL2)
CCC T681
HGNC 25842
MGI 1926022
PubMed 16391842
UniProt Q6UWX4
HHIPL2 is a 724 amino acid secreted protein that belongs to the HHIP family and is encoded by a gene which maps to human chromosome 1.When defective, the LMNA gene product can build up in the nucleus and cause characteristic nuclear blebs. The mechanism of rapidly enhanced aging is unclear and is a topic of continuing exploration. The MUTYH gene is located on chromosome 1 and is partially responsible for familial adenomatous polyposis. Stickler syndrome, Parkinsons, Gaucher disease and Usher syndrome are also associated with chromosome 1. A breakpoint has been identified in 1q which disrupts the DISC1 gene and is linked to schizophrenia. Aberrations in chromosome 1 are found in a variety of cancers including head and neck cancer, malignant melanoma and multiple myeloma.

Organism species: Homo sapiens (Human)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a Recombinant Hedgehog Interacting Protein Like Protein 2 (HHIPL2) Recombinant Protein Customized Service Offer
Antibodies n/a Monoclonal Antibody to Hedgehog Interacting Protein Like Protein 2 (HHIPL2) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to Hedgehog Interacting Protein Like Protein 2 (HHIPL2) Polyclonal Antibody Customized Service Offer
Assay Kits n/a CLIA Kit for Hedgehog Interacting Protein Like Protein 2 (HHIPL2) CLIA Kit Customized Service Offer
n/a ELISA Kit for Hedgehog Interacting Protein Like Protein 2 (HHIPL2) ELISA Kit Customized Service Offer

Organism species: Mus musculus (Mouse)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a Recombinant Hedgehog Interacting Protein Like Protein 2 (HHIPL2) Recombinant Protein Customized Service Offer
Antibodies n/a Monoclonal Antibody to Hedgehog Interacting Protein Like Protein 2 (HHIPL2) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to Hedgehog Interacting Protein Like Protein 2 (HHIPL2) Polyclonal Antibody Customized Service Offer
Assay Kits n/a CLIA Kit for Hedgehog Interacting Protein Like Protein 2 (HHIPL2) CLIA Kit Customized Service Offer
n/a ELISA Kit for Hedgehog Interacting Protein Like Protein 2 (HHIPL2) ELISA Kit Customized Service Offer
  1. "The secreted protein discovery initiative (SPDI), a large-scale effort to identify novel human secreted and transmembrane proteins: a bioinformatics assessment." Genome Res. 13:2265-2270(2003) [PubMed] [Europe PMC] [Abstract]
  2. "The DNA sequence and biological annotation of human chromosome 1." Nature 441:315-321(2006) [PubMed] [Europe PMC] [Abstract]
  3. "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
  4. "Complete sequencing and characterization of 21,243 full-length human cDNAs." Nat. Genet. 36:40-45(2004) [PubMed] [Europe PMC] [Abstract]
  5. "Comparative genomics on HHIP family orthologs."Int. J. Mol. Med. 17:391-395(2006) [PubMed] [Europe PMC] [Abstract]