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BH3 Only Protein (BOP)

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C22orf29

BH3 Only Protein (BOP)
CCC T691
HGNC 26112
UniProt Q7L3V2
Chromosome 22 contains over 500 genes and about 49 million bases. Being the second smallest human chromosome, 22 contains a surprising variety of interesting genes. Phelan-McDermid syndrome, neurofibromatosis type 2 and autism are associated with chromosome 22.
A schizophrenia susceptibility locus has been identified on chromosome 22 and studies show that 22q11 deletion symptoms include a high incidence of schizophrenia. Transloacations between chromosomes 9 and 22 may lead to the formation of the Philadelphia chromosome and the subsequent production of the novel fusion protein, Bcr-Abl, a potent cell proliferation activator found in several types of leukemia. The C22orf29 gene product has been provisionally designated C22orf29 pending further characterization.

Organism species: Homo sapiens (Human)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a Recombinant BH3 Only Protein (BOP) Recombinant Protein Customized Service Offer
Antibodies n/a Monoclonal Antibody to BH3 Only Protein (BOP) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to BH3 Only Protein (BOP) Polyclonal Antibody Customized Service Offer
Assay Kits n/a CLIA Kit for BH3 Only Protein (BOP) CLIA Kit Customized Service Offer
n/a ELISA Kit for BH3 Only Protein (BOP) ELISA Kit Customized Service Offer
  1. "Complete sequencing and characterization of 21,243 full-length human cDNAs." Nat. Genet. 36:40-45(2004) [PubMed] [Europe PMC] [Abstract]
  2. "The full-ORF clone resource of the German cDNA consortium."BMC Genomics 8:399-399(2007) [PubMed] [Europe PMC] [Abstract]
  3. "The DNA sequence of human chromosome 22." Nature 402:489-495(1999) [PubMed] [Europe PMC] [Abstract]
  4. "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
  5. "Human Bop is a novel BH3-only member of the Bcl-2 protein family."Protein Cell 3:790-801(2012) [PubMed] [Europe PMC] [Abstract]