≡

Spermatogenesis Associated Protein 20 (SPATA20)

[Edit]

Tisp78; Ssp411; Sperm-specific protein 411

Spermatogenesis Associated Protein 20 (SPATA20)
CCC T692
HGNC 26125
MGI 2183449
PubMed 23118872
RGD 735087
UniProt Q8TB22
SPATA20 is a 786 amino acid protein that may be involved in fertility regulation. SPATA20 is expressed in testes in an age dependent manner and localizes to round and elongated spermatids. SPATA20 contains a conserved thioredoxin-like domain near the N-terminus region and exists as four isoforms produced by alternative splicing events. SPATA20 is encoded by a gene located on human chromosome 17, which comprises over 2.5% of the human genome andencodes over 1,200 genes. Two key tumor suppressor genes are associated with chromosome 17, namely, p53 and BRCA1. Tumor suppressor p53 is necessary for maintenance of cellular genetic integrity by moderating cell fate through DNA repair versus cell death. Malfunction or loss of p53 expression is associated with malignant cell growth and Li-Fraumeni syndrome.

Organism species: Homo sapiens (Human)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a Recombinant Spermatogenesis Associated Protein 20 (SPATA20) Recombinant Protein Customized Service Offer
Antibodies n/a Monoclonal Antibody to Spermatogenesis Associated Protein 20 (SPATA20) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to Spermatogenesis Associated Protein 20 (SPATA20) Polyclonal Antibody Customized Service Offer
Assay Kits n/a CLIA Kit for Spermatogenesis Associated Protein 20 (SPATA20) CLIA Kit Customized Service Offer
n/a ELISA Kit for Spermatogenesis Associated Protein 20 (SPATA20) ELISA Kit Customized Service Offer

Organism species: Mus musculus (Mouse)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a Recombinant Spermatogenesis Associated Protein 20 (SPATA20) Recombinant Protein Customized Service Offer
Antibodies n/a Monoclonal Antibody to Spermatogenesis Associated Protein 20 (SPATA20) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to Spermatogenesis Associated Protein 20 (SPATA20) Polyclonal Antibody Customized Service Offer
Assay Kits n/a CLIA Kit for Spermatogenesis Associated Protein 20 (SPATA20) CLIA Kit Customized Service Offer
n/a ELISA Kit for Spermatogenesis Associated Protein 20 (SPATA20) ELISA Kit Customized Service Offer

Organism species: Rattus norvegicus (Rat)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a Recombinant Spermatogenesis Associated Protein 20 (SPATA20) Recombinant Protein Customized Service Offer
Antibodies n/a Monoclonal Antibody to Spermatogenesis Associated Protein 20 (SPATA20) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to Spermatogenesis Associated Protein 20 (SPATA20) Polyclonal Antibody Customized Service Offer
Assay Kits n/a CLIA Kit for Spermatogenesis Associated Protein 20 (SPATA20) CLIA Kit Customized Service Offer
n/a ELISA Kit for Spermatogenesis Associated Protein 20 (SPATA20) ELISA Kit Customized Service Offer
  1. "Complete sequencing and characterization of 21,243 full-length human cDNAs." Nat. Genet. 36:40-45(2004) [PubMed] [Europe PMC] [Abstract]
  2. "DNA sequence of human chromosome 17 and analysis of rearrangement in the human lineage." Nature 440:1045-1049(2006) [PubMed] [Europe PMC] [Abstract]
  3. "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]