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Sesquipedalian 2 (Ses2)

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FAM109B; IPIP27B; 27 kDa inositol polyphosphate phosphatase interacting protein B; Family With Sequence Similarity 109, Member B

Sesquipedalian 2 (Ses2)
CCC T715
HGNC 27161
MGI 2443609
PubMed 20133602
RGD 1586415
UniProt Q6ICB4
The 259 amino acid protein is encoded by a gene on chromosome 22. Chromosome 22 contains over 500 genes and about 49 million bases. Being the second smallest human chromosome, 22 contains a surprising variety of interesting genes. Phelan-McDermid syndrome, neurofibromatosis type 2 and autism are associated with chromosome 22. A schizophrenia susceptibility locus has been identified on chromosome 22 and studies show that 22q11 deletion symptoms include a high incidence of schizophrenia. Translocations between chromosomes 9 and 22 may lead to the formation of the Philadelphia chromosome and the subsequent production of the novel fusion protein, Bcr-Abl, a potent cell proliferation activator found in several types of leukemia.

Organism species: Homo sapiens (Human)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a Recombinant Sesquipedalian 2 (Ses2) Recombinant Protein Customized Service Offer
Antibodies n/a Monoclonal Antibody to Sesquipedalian 2 (Ses2) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to Sesquipedalian 2 (Ses2) Polyclonal Antibody Customized Service Offer
Assay Kits n/a CLIA Kit for Sesquipedalian 2 (Ses2) CLIA Kit Customized Service Offer
n/a ELISA Kit for Sesquipedalian 2 (Ses2) ELISA Kit Customized Service Offer

Organism species: Mus musculus (Mouse)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a Recombinant Sesquipedalian 2 (Ses2) Recombinant Protein Customized Service Offer
Antibodies n/a Monoclonal Antibody to Sesquipedalian 2 (Ses2) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to Sesquipedalian 2 (Ses2) Polyclonal Antibody Customized Service Offer
Assay Kits n/a CLIA Kit for Sesquipedalian 2 (Ses2) CLIA Kit Customized Service Offer
n/a ELISA Kit for Sesquipedalian 2 (Ses2) ELISA Kit Customized Service Offer

Organism species: Rattus norvegicus (Rat)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a Recombinant Sesquipedalian 2 (Ses2) Recombinant Protein Customized Service Offer
Antibodies n/a Monoclonal Antibody to Sesquipedalian 2 (Ses2) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to Sesquipedalian 2 (Ses2) Polyclonal Antibody Customized Service Offer
Assay Kits n/a CLIA Kit for Sesquipedalian 2 (Ses2) CLIA Kit Customized Service Offer
n/a ELISA Kit for Sesquipedalian 2 (Ses2) ELISA Kit Customized Service Offer
  1. "A genome annotation-driven approach to cloning the human ORFeome."Genome Biol. 5:R84.1-R84.11(2004) [PubMed] [Europe PMC] [Abstract]
  2. "The DNA sequence of human chromosome 22." Nature 402:489-495(1999) [PubMed] [Europe PMC] [Abstract]
  3. "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
  4. "Two closely related endocytic proteins that share a common OCRL-binding motif with APPL1."Proc. Natl. Acad. Sci. U.S.A. 107:3511-3516(2010) [PubMed] [Europe PMC] [Abstract]
  5. "The PH domain proteins IPIP27A and B link OCRL1 to receptor recycling in the endocytic pathway."Mol. Biol. Cell 22:606-623(2011) [PubMed] [Europe PMC] [Abstract]