LIMD2 belongs to the LIM only family of LIM proteins and was identified as one of biomarkers for papillary thyroid carcinoma lymph node metastasis from molecular profiling of matched samples. However, the biological function of LIMD2 remains unknown. To identify if the LIMD2 is biomarker for other cancers, highly specific LIMD2 polyclonal and monoclonal antibodies have been developed and several cancer cell lines were tested for LIMD2 expression. The cancer cell lines were derived from breast cancer, melanoma, bladder cancer, and thyroid cancer. The data show that the higher level of transcription and expression of LIMD2 are correlated with the more aggressive cancer cell lines. The migration assay indicated the higher level of expression of LIMD2 was also correlated with the higher degree of migration.
Organism species: Homo sapiens (Human)
CATALOG NO. | PRODUCT NAME | APPLICATIONS | |
Proteins | n/a | Recombinant LIM Domains Containing Protein 2 (LIMD2) | Recombinant Protein Customized Service Offer |
Antibodies | n/a | Monoclonal Antibody to LIM Domains Containing Protein 2 (LIMD2) | Monoclonal Antibody Customized Service Offer |
n/a | Polyclonal Antibody to LIM Domains Containing Protein 2 (LIMD2) | Polyclonal Antibody Customized Service Offer | |
Assay Kits | n/a | CLIA Kit for LIM Domains Containing Protein 2 (LIMD2) | CLIA Kit Customized Service Offer |
n/a | ELISA Kit for LIM Domains Containing Protein 2 (LIMD2) | ELISA Kit Customized Service Offer |
Organism species: Mus musculus (Mouse)
CATALOG NO. | PRODUCT NAME | APPLICATIONS | |
Proteins | n/a | Recombinant LIM Domains Containing Protein 2 (LIMD2) | Recombinant Protein Customized Service Offer |
Antibodies | n/a | Monoclonal Antibody to LIM Domains Containing Protein 2 (LIMD2) | Monoclonal Antibody Customized Service Offer |
n/a | Polyclonal Antibody to LIM Domains Containing Protein 2 (LIMD2) | Polyclonal Antibody Customized Service Offer | |
Assay Kits | n/a | CLIA Kit for LIM Domains Containing Protein 2 (LIMD2) | CLIA Kit Customized Service Offer |
n/a | ELISA Kit for LIM Domains Containing Protein 2 (LIMD2) | ELISA Kit Customized Service Offer |
Organism species: Rattus norvegicus (Rat)
CATALOG NO. | PRODUCT NAME | APPLICATIONS | |
Proteins | n/a | Recombinant LIM Domains Containing Protein 2 (LIMD2) | Recombinant Protein Customized Service Offer |
Antibodies | n/a | Monoclonal Antibody to LIM Domains Containing Protein 2 (LIMD2) | Monoclonal Antibody Customized Service Offer |
n/a | Polyclonal Antibody to LIM Domains Containing Protein 2 (LIMD2) | Polyclonal Antibody Customized Service Offer | |
Assay Kits | n/a | CLIA Kit for LIM Domains Containing Protein 2 (LIMD2) | CLIA Kit Customized Service Offer |
n/a | ELISA Kit for LIM Domains Containing Protein 2 (LIMD2) | ELISA Kit Customized Service Offer |
- "Complete sequencing and characterization of 21,243 full-length human cDNAs." Nat. Genet. 36:40-45(2004) [PubMed] [Europe PMC] [Abstract]
- "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
- "Lys-N and trypsin cover complementary parts of the phosphoproteome in a refined SCX-based approach."Anal. Chem. 81:4493-4501(2009) [PubMed] [Europe PMC] [Abstract]
- "Initial characterization of the human central proteome."BMC Syst. Biol. 5:17-17(2011) [PubMed] [Europe PMC] [Abstract]