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Ring Finger Protein, Transmembrane 1 (RNFT1)

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PTD016; RING finger and transmembrane domain-containing protein 1

Ring Finger Protein, Transmembrane 1 (RNFT1)
CCC T768
HGNC 30206
MGI 1924142
RGD 1562411
UniProt Q5M7Z0
Two key tumor suppressor genes are associated with chromosome 17, namely, p53 and . Tumor suppressor p53 is necessary for maintenance of cellular genetic integrity by moderating cell fate through DNA repair versus cell death. Malfunction or loss of p53 expression is associated with malignant cell growth and Li-Fraumeni syndrome. Like p53, BRCA1 is directly involved in DNA repair, though specifically it is recognized as a genetic determinant of early onset breast cancer and predisposition to cancers of the ovary, colon, prostate gland and fallopian tubes. Chromosome 17 is also linked to neurofibromatosis, a condition characterized by neural and epidermal lesions, and dysregulated Schwann cell growth. Alexander disease, Birt-Hogg-Dube syndrome and Canavan disease are also associated with chromosome 17.

Organism species: Homo sapiens (Human)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a Recombinant Ring Finger Protein, Transmembrane 1 (RNFT1) Recombinant Protein Customized Service Offer
Antibodies n/a Monoclonal Antibody to Ring Finger Protein, Transmembrane 1 (RNFT1) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to Ring Finger Protein, Transmembrane 1 (RNFT1) Polyclonal Antibody Customized Service Offer
Assay Kits n/a CLIA Kit for Ring Finger Protein, Transmembrane 1 (RNFT1) CLIA Kit Customized Service Offer
n/a ELISA Kit for Ring Finger Protein, Transmembrane 1 (RNFT1) ELISA Kit Customized Service Offer

Organism species: Mus musculus (Mouse)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a Recombinant Ring Finger Protein, Transmembrane 1 (RNFT1) Recombinant Protein Customized Service Offer
Antibodies n/a Monoclonal Antibody to Ring Finger Protein, Transmembrane 1 (RNFT1) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to Ring Finger Protein, Transmembrane 1 (RNFT1) Polyclonal Antibody Customized Service Offer
Assay Kits n/a CLIA Kit for Ring Finger Protein, Transmembrane 1 (RNFT1) CLIA Kit Customized Service Offer
n/a ELISA Kit for Ring Finger Protein, Transmembrane 1 (RNFT1) ELISA Kit Customized Service Offer

Organism species: Rattus norvegicus (Rat)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a Recombinant Ring Finger Protein, Transmembrane 1 (RNFT1) Recombinant Protein Customized Service Offer
Antibodies n/a Monoclonal Antibody to Ring Finger Protein, Transmembrane 1 (RNFT1) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to Ring Finger Protein, Transmembrane 1 (RNFT1) Polyclonal Antibody Customized Service Offer
Assay Kits n/a CLIA Kit for Ring Finger Protein, Transmembrane 1 (RNFT1) CLIA Kit Customized Service Offer
n/a ELISA Kit for Ring Finger Protein, Transmembrane 1 (RNFT1) ELISA Kit Customized Service Offer
  1. "DNA sequence of human chromosome 17 and analysis of rearrangement in the human lineage." Nature 440:1045-1049(2006) [PubMed] [Europe PMC] [Abstract]
  2. "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
  3. "Complete sequencing and characterization of 21,243 full-length human cDNAs." Nat. Genet. 36:40-45(2004) [PubMed] [Europe PMC] [Abstract]
  4. "Identification of ten novel genes involved in human spermatogenesis by microarray analysis of testicular tissue."Fertil. Steril. 86:1650-1658(2006) [PubMed] [Europe PMC] [Abstract]