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MCF2 Cell Line Derived Transforming Sequence Like Protein 2 (MCF2L2)

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ARHGEF22; DRG; Dbs-related Rho family guanine nucleotide exchange factor; Probable guanine nucleotide exchange factor MCF2L2

MCF2 Cell Line Derived Transforming Sequence Like Protein 2 (MCF2L2)
CCC T770
HGNC 30319
UniProt Q86YR7
MCF2L2, ADIPOQ and SOX2 genes are located in chromosome 3q26-27, which is linked to diabetic nephropathy (DN). ADIPOQ and SOX2 genetic polymorphisms are found to be associated with DN.
Leu359Ile T/G variant in the MCF2L2 gene was found to be associated with DN in female subjects but not in males. The GG genotype carriers among female patients with DN had tendency decreased creatinine and cystatin levels compared to the carriers with either TT or TG genotypes. MCF2L2, ADIPOQ and SOX2 genetic polymorphisms have effects on the resistance of DN in female T1D patients, and suggests that the linkage with DN in chromosome 3q may be explained by the cumulated genetic effects.

Organism species: Homo sapiens (Human)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a Recombinant MCF2 Cell Line Derived Transforming Sequence Like Protein 2 (MCF2L2) Recombinant Protein Customized Service Offer
Antibodies n/a Monoclonal Antibody to MCF2 Cell Line Derived Transforming Sequence Like Protein 2 (MCF2L2) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to MCF2 Cell Line Derived Transforming Sequence Like Protein 2 (MCF2L2) Polyclonal Antibody Customized Service Offer
Assay Kits n/a CLIA Kit for MCF2 Cell Line Derived Transforming Sequence Like Protein 2 (MCF2L2) CLIA Kit Customized Service Offer
n/a ELISA Kit for MCF2 Cell Line Derived Transforming Sequence Like Protein 2 (MCF2L2) ELISA Kit Customized Service Offer

Organism species: Mus musculus (Mouse)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a Recombinant MCF2 Cell Line Derived Transforming Sequence Like Protein 2 (MCF2L2) Recombinant Protein Customized Service Offer
Antibodies n/a Monoclonal Antibody to MCF2 Cell Line Derived Transforming Sequence Like Protein 2 (MCF2L2) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to MCF2 Cell Line Derived Transforming Sequence Like Protein 2 (MCF2L2) Polyclonal Antibody Customized Service Offer
Assay Kits n/a CLIA Kit for MCF2 Cell Line Derived Transforming Sequence Like Protein 2 (MCF2L2) CLIA Kit Customized Service Offer
n/a ELISA Kit for MCF2 Cell Line Derived Transforming Sequence Like Protein 2 (MCF2L2) ELISA Kit Customized Service Offer
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