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Alkylglycerol Monooxygenase (AGMO)

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TMEM195; Transmembrane Protein 195

Alkylglycerol Monooxygenase (AGMO)
CCC T813
HGNC 33784
MGI 2442495
PubMed 23441072
RGD 1312038
UniProt Q6ZNB7
Wiki AGMO
Alkylglycerol monooxygenase (AGMO) cleaves the O-alkyl bonds of ether lipids, which are essential components of brain membranes and function in cell signaling and other critical biologic processes. The reaction catalyzed by AGMO is dependent on tetrahydrobiopterin, a metabolite structurally related to the vitamins folic acid and riboflavin.
The fatty acid hydroxylase motif consists of 8 conserved histidines that are predicted to bind iron atoms in a catalytic diiron center. In silico analysis suggested that expression of Tmem195 is highest in mouse liver and small intestine, consistent with elevated endogenous alkylglycerol monooxygenase activity in these tissues. Fluorescence-tagged TMEM195 localized to the endoplasmic reticulum in transfected cells.

Organism species: Homo sapiens (Human)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a Recombinant Alkylglycerol Monooxygenase (AGMO) Recombinant Protein Customized Service Offer
Antibodies n/a Monoclonal Antibody to Alkylglycerol Monooxygenase (AGMO) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to Alkylglycerol Monooxygenase (AGMO) Polyclonal Antibody Customized Service Offer
Assay Kits n/a CLIA Kit for Alkylglycerol Monooxygenase (AGMO) CLIA Kit Customized Service Offer
n/a ELISA Kit for Alkylglycerol Monooxygenase (AGMO) ELISA Kit Customized Service Offer

Organism species: Mus musculus (Mouse)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a Recombinant Alkylglycerol Monooxygenase (AGMO) Recombinant Protein Customized Service Offer
Antibodies n/a Monoclonal Antibody to Alkylglycerol Monooxygenase (AGMO) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to Alkylglycerol Monooxygenase (AGMO) Polyclonal Antibody Customized Service Offer
Assay Kits n/a CLIA Kit for Alkylglycerol Monooxygenase (AGMO) CLIA Kit Customized Service Offer
n/a ELISA Kit for Alkylglycerol Monooxygenase (AGMO) ELISA Kit Customized Service Offer

Organism species: Rattus norvegicus (Rat)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a Recombinant Alkylglycerol Monooxygenase (AGMO) Recombinant Protein Customized Service Offer
Antibodies n/a Monoclonal Antibody to Alkylglycerol Monooxygenase (AGMO) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to Alkylglycerol Monooxygenase (AGMO) Polyclonal Antibody Customized Service Offer
Assay Kits n/a CLIA Kit for Alkylglycerol Monooxygenase (AGMO) CLIA Kit Customized Service Offer
n/a ELISA Kit for Alkylglycerol Monooxygenase (AGMO) ELISA Kit Customized Service Offer
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  4. "Identification of the gene encoding alkylglycerol monooxygenase defines a third class of tetrahydrobiopterin-dependent enzymes."Proc. Natl. Acad. Sci. U.S.A. 107:13672-13677(2010) [PubMed] [Europe PMC] [Abstract]
  5. "An enzyme assisted RP-RPLC approach for in-depth analysis of human liver phosphoproteome."J. Proteomics 96:253-262(2014) [PubMed] [Europe PMC] [Abstract]