Chromosome 11 Open Reading Frame 16 (C11orf16)

C11orf16 is moderately expressed, only 32.3% of the average gene in this release. The sequence similarity between human and mouse is higher in transcribed and exon regions than in non-transcribed segments. In particular, the positions of CpG islands, short regions of very high GC content in the 5' region of putative genes, are similar in human and mouse. With respect to base composition, two distinct segments of significantly different GC content exist as well in human as in the mouse. The gene density is slightly higher than the average calculated for the complete human genome. The comparison of the number and distribution of repetitive elements shows that the proportion of human DNA made up by interspersed repeats is significantly higher than in the corresponding mouse DNA.