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Zinc Finger Protein 462 (ZNF462)

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Zfp462

Zinc Finger Protein 462 (ZNF462)
CCC U065
HGNC 21684
MGI 107690
PubMed 17632789
RGD 1562123
UniProt Q96JM2
ZNF462, May be involved in transcriptional regulation. Belongs to the krueppel C2H2-type zinc-finger protein family.Contains 27 C2H2-type zinc fingers. Phosphorylated upon DNA damage, probably by ATM or ATR.
A zinc finger protein is a DNA-binding protein domain consisting of zinc fingers ranging from two in the Drosophila regulator ADR1, the more common three in mammalian Sp1 up to nine in TFIIIA. They occur in nature as the part of transcription factors conferring DNA sequence specificity as the DNA-binding domain. They have also found use in protein engineering due to their modularity and have prospects as components of tools for use in therapeutic gene modulation and zinc finger nucleases. Zinc finger protein consists of anti-parallel hairpin motif. It consists of 2 beta strands, one alpha helix and a hairpin structure.

Organism species: Homo sapiens (Human)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a Recombinant Zinc Finger Protein 462 (ZNF462) Recombinant Protein Customized Service Offer
Antibodies n/a Monoclonal Antibody to Zinc Finger Protein 462 (ZNF462) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to Zinc Finger Protein 462 (ZNF462) Polyclonal Antibody Customized Service Offer
Assay Kits n/a CLIA Kit for Zinc Finger Protein 462 (ZNF462) CLIA Kit Customized Service Offer
n/a ELISA Kit for Zinc Finger Protein 462 (ZNF462) ELISA Kit Customized Service Offer

Organism species: Mus musculus (Mouse)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a Recombinant Zinc Finger Protein 462 (ZNF462) Recombinant Protein Customized Service Offer
Antibodies n/a Monoclonal Antibody to Zinc Finger Protein 462 (ZNF462) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to Zinc Finger Protein 462 (ZNF462) Polyclonal Antibody Customized Service Offer
Assay Kits n/a CLIA Kit for Zinc Finger Protein 462 (ZNF462) CLIA Kit Customized Service Offer
n/a ELISA Kit for Zinc Finger Protein 462 (ZNF462) ELISA Kit Customized Service Offer

Organism species: Rattus norvegicus (Rat)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a Recombinant Zinc Finger Protein 462 (ZNF462) Recombinant Protein Customized Service Offer
Antibodies n/a Monoclonal Antibody to Zinc Finger Protein 462 (ZNF462) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to Zinc Finger Protein 462 (ZNF462) Polyclonal Antibody Customized Service Offer
Assay Kits n/a CLIA Kit for Zinc Finger Protein 462 (ZNF462) CLIA Kit Customized Service Offer
n/a ELISA Kit for Zinc Finger Protein 462 (ZNF462) ELISA Kit Customized Service Offer
  1. "Prediction of the coding sequences of unidentified human genes. XX. The complete sequences of 100 new cDNA clones from brain which code for large proteins in vitro."DNA Res. 8:85-95(2001) [PubMed] [Europe PMC] [Abstract]
  2. "Construction of expression-ready cDNA clones for KIAA genes: manual curation of 330 KIAA cDNA clones."DNA Res. 9:99-106(2002) [PubMed] [Europe PMC] [Abstract]
  3. "DNA sequence and analysis of human chromosome 9." Nature 429:369-374(2004) [PubMed] [Europe PMC] [Abstract]
  4. "Complete sequencing and characterization of 21,243 full-length human cDNAs." Nat. Genet. 36:40-45(2004) [PubMed] [Europe PMC] [Abstract]
  5. "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
  6. "Quantitative phosphoproteomic analysis of T cell receptor signaling reveals system-wide modulation of protein-protein interactions."Sci. Signal. 2:RA46-RA46(2009) [PubMed] [Europe PMC] [Abstract]
  7. "System-wide temporal characterization of the proteome and phosphoproteome of human embryonic stem cell differentiation."Sci. Signal. 4:RS3-RS3(2011) [PubMed] [Europe PMC] [Abstract]
  8. "Discovery of O-GlcNAc-6-phosphate modified proteins in large-scale phosphoproteomics data."Mol. Cell. Proteomics 11:1063-1069(2012) [PubMed] [Europe PMC] [Abstract]
  9. "Solution structures of the C2H2 type zinc finger domain of human zinc finger protein 462."Submitted (NOV-2005) to the PDB data bank