Leucine Rich Repeat Immunoglobulin Like And Transmembrane Domains Protein 3 (LRIT3)
[Edit]FIGLER4; Fibronectin Type III, Immunoglobulin And Leucine Rich Repeat Domains 4
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LRIT3 Contains 1 fibronectin type-III domain.Contains 1 Ig-like (immunoglobulin-like) domain.Contains 4 LRR (leucine-rich) repeats.Contains 1 LRRCT domain.
A leucine-rich repeat (LRR) is a protein structural motif that forms an α/β horseshoe fold.[1][2] It is composed of repeating 20–30 amino acid stretches that are unusually rich in the hydrophobic amino acid leucine. Typically, each repeat unit has beta strand-turn-alpha helix structure, and the assembled domain, composed of many such repeats, has a horseshoe shape with an interior parallel beta sheet and an exterior array of helices. One face of the beta sheet and one side of the helix array are exposed to solvent and are therefore dominated by hydrophilic residues.
A leucine-rich repeat (LRR) is a protein structural motif that forms an α/β horseshoe fold.[1][2] It is composed of repeating 20–30 amino acid stretches that are unusually rich in the hydrophobic amino acid leucine. Typically, each repeat unit has beta strand-turn-alpha helix structure, and the assembled domain, composed of many such repeats, has a horseshoe shape with an interior parallel beta sheet and an exterior array of helices. One face of the beta sheet and one side of the helix array are exposed to solvent and are therefore dominated by hydrophilic residues.
Organism species: Homo sapiens (Human)
| CATALOG NO. | PRODUCT NAME | APPLICATIONS | |
| Proteins | n/a | Recombinant Leucine Rich Repeat Immunoglobulin Like And Transmembrane Domains Protein 3 (LRIT3) | Recombinant Protein Customized Service Offer |
| Antibodies | n/a | Monoclonal Antibody to Leucine Rich Repeat Immunoglobulin Like And Transmembrane Domains Protein 3 (LRIT3) | Monoclonal Antibody Customized Service Offer |
| n/a | Polyclonal Antibody to Leucine Rich Repeat Immunoglobulin Like And Transmembrane Domains Protein 3 (LRIT3) | Polyclonal Antibody Customized Service Offer | |
| Assay Kits | n/a | CLIA Kit for Leucine Rich Repeat Immunoglobulin Like And Transmembrane Domains Protein 3 (LRIT3) | CLIA Kit Customized Service Offer |
| n/a | ELISA Kit for Leucine Rich Repeat Immunoglobulin Like And Transmembrane Domains Protein 3 (LRIT3) | ELISA Kit Customized Service Offer |
Organism species: Mus musculus (Mouse)
| CATALOG NO. | PRODUCT NAME | APPLICATIONS | |
| Proteins | n/a | Recombinant Leucine Rich Repeat Immunoglobulin Like And Transmembrane Domains Protein 3 (LRIT3) | Recombinant Protein Customized Service Offer |
| Antibodies | n/a | Monoclonal Antibody to Leucine Rich Repeat Immunoglobulin Like And Transmembrane Domains Protein 3 (LRIT3) | Monoclonal Antibody Customized Service Offer |
| n/a | Polyclonal Antibody to Leucine Rich Repeat Immunoglobulin Like And Transmembrane Domains Protein 3 (LRIT3) | Polyclonal Antibody Customized Service Offer | |
| Assay Kits | n/a | CLIA Kit for Leucine Rich Repeat Immunoglobulin Like And Transmembrane Domains Protein 3 (LRIT3) | CLIA Kit Customized Service Offer |
| n/a | ELISA Kit for Leucine Rich Repeat Immunoglobulin Like And Transmembrane Domains Protein 3 (LRIT3) | ELISA Kit Customized Service Offer |
Organism species: Rattus norvegicus (Rat)
| CATALOG NO. | PRODUCT NAME | APPLICATIONS | |
| Proteins | n/a | Recombinant Leucine Rich Repeat Immunoglobulin Like And Transmembrane Domains Protein 3 (LRIT3) | Recombinant Protein Customized Service Offer |
| Antibodies | n/a | Monoclonal Antibody to Leucine Rich Repeat Immunoglobulin Like And Transmembrane Domains Protein 3 (LRIT3) | Monoclonal Antibody Customized Service Offer |
| n/a | Polyclonal Antibody to Leucine Rich Repeat Immunoglobulin Like And Transmembrane Domains Protein 3 (LRIT3) | Polyclonal Antibody Customized Service Offer | |
| Assay Kits | n/a | CLIA Kit for Leucine Rich Repeat Immunoglobulin Like And Transmembrane Domains Protein 3 (LRIT3) | CLIA Kit Customized Service Offer |
| n/a | ELISA Kit for Leucine Rich Repeat Immunoglobulin Like And Transmembrane Domains Protein 3 (LRIT3) | ELISA Kit Customized Service Offer |
- "Complete sequencing and characterization of 21,243 full-length human cDNAs." Nat. Genet. 36:40-45(2004) [PubMed] [Europe PMC] [Abstract]
- "Generation and annotation of the DNA sequences of human chromosomes 2 and 4." Nature 434:724-731(2005) [PubMed] [Europe PMC] [Abstract]
- "Leucine-rich repeat, immunoglobulin-like and transmembrane domain 3 (LRIT3) is a modulator of FGFR1."FEBS Lett. 586:1516-1521(2012) [PubMed] [Europe PMC] [Abstract]
- "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
- "Whole-exome sequencing identifies LRIT3 mutations as a cause of autosomal-recessive complete congenital stationary night blindness." Am. J. Hum. Genet. 92:67-75(2013) [PubMed] [Europe PMC] [Abstract]