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Family With Sequence Similarity 125, Member A (FAM125A)

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MVB12A; CFBP; Multivesicular Body Subunit 12A; CIN85/CD2AP Family-Binding Protein; ESCRT-I complex subunit MVB12A

Family With Sequence Similarity 125, Member A (FAM125A)
CCC U236
HGNC 25153
MGI 1920961
PubMed 23279575
RGD 735220
UniProt Q96EY5
FAM125A Belongs to the FAM125 family.Contains 1 MABP domain.Contains 1 UMA domain. Ubiquitously expressed except in skeletal muscle.Component of the ESCRT-I complex which consists of TSG101, VPS28, a VPS37 protein and a FAM125/MVB12 protein in a 1:1:1:1 stoechiometry. Interacts with CD2AP and CIN85/SH3KBP1. Interacts with CD2AP (via one of the SH3 domains). Interacts with TSG101; the association appears to be mediated by the TSG101-VPS37 binary subcomplex. Interacts with VPS28. Interacts with VPS37B; the association appears to be mediated by the TSG101-VPS37 binary subcomplex. Interacts with VPS37C; the association appears to be mediated by the TSG101-VPS37 binary subcomplex. Interacts with VPS37D; the association appears to be mediated by the TSG101-VPS37 binary subcomplex. Interacts with CEP55.

Organism species: Homo sapiens (Human)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a Recombinant Family With Sequence Similarity 125, Member A (FAM125A) Recombinant Protein Customized Service Offer
Antibodies n/a Monoclonal Antibody to Family With Sequence Similarity 125, Member A (FAM125A) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to Family With Sequence Similarity 125, Member A (FAM125A) Polyclonal Antibody Customized Service Offer
Assay Kits n/a CLIA Kit for Family With Sequence Similarity 125, Member A (FAM125A) CLIA Kit Customized Service Offer
n/a ELISA Kit for Family With Sequence Similarity 125, Member A (FAM125A) ELISA Kit Customized Service Offer

Organism species: Mus musculus (Mouse)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a Recombinant Family With Sequence Similarity 125, Member A (FAM125A) Recombinant Protein Customized Service Offer
Antibodies n/a Monoclonal Antibody to Family With Sequence Similarity 125, Member A (FAM125A) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to Family With Sequence Similarity 125, Member A (FAM125A) Polyclonal Antibody Customized Service Offer
Assay Kits n/a CLIA Kit for Family With Sequence Similarity 125, Member A (FAM125A) CLIA Kit Customized Service Offer
n/a ELISA Kit for Family With Sequence Similarity 125, Member A (FAM125A) ELISA Kit Customized Service Offer

Organism species: Rattus norvegicus (Rat)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a Recombinant Family With Sequence Similarity 125, Member A (FAM125A) Recombinant Protein Customized Service Offer
Antibodies n/a Monoclonal Antibody to Family With Sequence Similarity 125, Member A (FAM125A) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to Family With Sequence Similarity 125, Member A (FAM125A) Polyclonal Antibody Customized Service Offer
Assay Kits n/a CLIA Kit for Family With Sequence Similarity 125, Member A (FAM125A) CLIA Kit Customized Service Offer
n/a ELISA Kit for Family With Sequence Similarity 125, Member A (FAM125A) ELISA Kit Customized Service Offer
  1. "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
  2. "CFBP is a novel tyrosine-phosphorylated protein that might function as a regulator of CIN85/CD2AP."J. Biol. Chem. 281:28919-28931(2006) [PubMed] [Europe PMC] [Abstract]
  3. "A probability-based approach for high-throughput protein phosphorylation analysis and site localization."Nat. Biotechnol. 24:1285-1292(2006) [PubMed] [Europe PMC] [Abstract]
  4. "Identification of human MVB12 proteins as ESCRT-I subunits that function in HIV budding."Cell Host Microbe 2:41-53(2007) [PubMed] [Europe PMC] [Abstract]
  5. "Human ESCRT and ALIX proteins interact with proteins of the midbody and function in cytokinesis."EMBO J. 26:4215-4227(2007) [PubMed] [Europe PMC] [Abstract]
  6. "A quantitative atlas of mitotic phosphorylation."Proc. Natl. Acad. Sci. U.S.A. 105:10762-10767(2008) [PubMed] [Europe PMC] [Abstract]
  7. "Quantitative phosphoproteomic analysis of T cell receptor signaling reveals system-wide modulation of protein-protein interactions."Sci. Signal. 2:RA46-RA46(2009) [PubMed] [Europe PMC] [Abstract]
  8. "Quantitative phosphoproteomics reveals widespread full phosphorylation site occupancy during mitosis."Sci. Signal. 3:RA3-RA3(2010) [PubMed] [Europe PMC] [Abstract]
  9. "Initial characterization of the human central proteome."BMC Syst. Biol. 5:17-17(2011) [PubMed] [Europe PMC] [Abstract]
  10. "System-wide temporal characterization of the proteome and phosphoproteome of human embryonic stem cell differentiation."Sci. Signal. 4:RS3-RS3(2011) [PubMed] [Europe PMC] [Abstract]