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MAP7 Domain Containing Protein 3 (MAP7D3)

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MDP3

MAP7 Domain Containing Protein 3 (MAP7D3)
CCC U346
HGNC 25742
MGI 2445051
UniProt Q8IWC1
MAP7D3 belongs to the MAP7 (microtubule-associated protein 7) family. Alternatively spliced transcript variants encoding different isoforms have been found.
MAP7 Microtubule-stabilizing protein that may play an important role during reorganization of microtubules during polarization and differentiation of epithelial cells. Associates with microtubules in a dynamic manner. May play a role in the formation of intercellular contacts. Colocalization with TRPV4 results in the redistribution of TRPV4 toward the membrane and may link cytoskeletal microfilaments. Belongs to the MAP7 family. Up-regulated upon terminal differentiation of primary keratinocytes. Interacts with TRPV4. 3 isoforms of the human protein are produced by alternative splicing. Expressed in the skin and cells of epithelial origin.

Organism species: Homo sapiens (Human)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a Recombinant MAP7 Domain Containing Protein 3 (MAP7D3) Recombinant Protein Customized Service Offer
Antibodies n/a Monoclonal Antibody to MAP7 Domain Containing Protein 3 (MAP7D3) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to MAP7 Domain Containing Protein 3 (MAP7D3) Polyclonal Antibody Customized Service Offer
Assay Kits n/a CLIA Kit for MAP7 Domain Containing Protein 3 (MAP7D3) CLIA Kit Customized Service Offer
n/a ELISA Kit for MAP7 Domain Containing Protein 3 (MAP7D3) ELISA Kit Customized Service Offer

Organism species: Mus musculus (Mouse)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a Recombinant MAP7 Domain Containing Protein 3 (MAP7D3) Recombinant Protein Customized Service Offer
Antibodies n/a Monoclonal Antibody to MAP7 Domain Containing Protein 3 (MAP7D3) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to MAP7 Domain Containing Protein 3 (MAP7D3) Polyclonal Antibody Customized Service Offer
Assay Kits n/a CLIA Kit for MAP7 Domain Containing Protein 3 (MAP7D3) CLIA Kit Customized Service Offer
n/a ELISA Kit for MAP7 Domain Containing Protein 3 (MAP7D3) ELISA Kit Customized Service Offer
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  11. "Mdp3 is a novel microtubule-binding protein that regulates microtubule assembly and stability."Cell Cycle 10:3929-3937(2011) [PubMed] [Europe PMC] [Abstract]
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  14. "C-terminal region of MAP7 domain containing protein 3 (MAP7D3) promotes microtubule polymerization by binding at the C-terminal tail of tubulin."PLoS ONE 9:E99539-E99539(2014) [PubMed] [Europe PMC] [Abstract]