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Prospero Homeobox Protein 2 (PROX2)

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Homeobox prospero-like protein PROX2

Prospero Homeobox Protein 2 (PROX2)
CCC U535
HGNC 26715
MGI 1920672
RGD 1310315
UniProt Q3B8N5
PROX2 Belongs to the Prospero homeobox family.Contains 1 Prospero-type homeobox DNA-binding domain.Transcription regulator. Does not seem to be essential for embryonic development and postnatal survival.
The prospero domain coincides with a domain in a Drosophila gene that is expressed in Drosophila central nervous system and in the developing lens-secreting cone cells of the eye. Exon 1 of the human sequence showed no clear similarity to the 3 alternatively spliced variants of chicken PROX1 cDNA. Human PROX1 exon 1 was found to contain repetitive sequences. Analysis of mRNA revealed that Prox mRNA was present in many different human tissues and that lens demonstrated the highest level. In all tissues but lens, PROX1 cDNA hybridized to a single band of 8 kb.

Organism species: Homo sapiens (Human)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a Recombinant Prospero Homeobox Protein 2 (PROX2) Recombinant Protein Customized Service Offer
Antibodies n/a Monoclonal Antibody to Prospero Homeobox Protein 2 (PROX2) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to Prospero Homeobox Protein 2 (PROX2) Polyclonal Antibody Customized Service Offer
Assay Kits n/a CLIA Kit for Prospero Homeobox Protein 2 (PROX2) CLIA Kit Customized Service Offer
n/a ELISA Kit for Prospero Homeobox Protein 2 (PROX2) ELISA Kit Customized Service Offer

Organism species: Mus musculus (Mouse)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a Recombinant Prospero Homeobox Protein 2 (PROX2) Recombinant Protein Customized Service Offer
Antibodies n/a Monoclonal Antibody to Prospero Homeobox Protein 2 (PROX2) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to Prospero Homeobox Protein 2 (PROX2) Polyclonal Antibody Customized Service Offer
Assay Kits n/a CLIA Kit for Prospero Homeobox Protein 2 (PROX2) CLIA Kit Customized Service Offer
n/a ELISA Kit for Prospero Homeobox Protein 2 (PROX2) ELISA Kit Customized Service Offer

Organism species: Rattus norvegicus (Rat)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a Recombinant Prospero Homeobox Protein 2 (PROX2) Recombinant Protein Customized Service Offer
Antibodies n/a Monoclonal Antibody to Prospero Homeobox Protein 2 (PROX2) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to Prospero Homeobox Protein 2 (PROX2) Polyclonal Antibody Customized Service Offer
Assay Kits n/a CLIA Kit for Prospero Homeobox Protein 2 (PROX2) CLIA Kit Customized Service Offer
n/a ELISA Kit for Prospero Homeobox Protein 2 (PROX2) ELISA Kit Customized Service Offer
  1. "The DNA sequence and analysis of human chromosome 14." Nature 421:601-607(2003) [PubMed] [Europe PMC] [Abstract]
  2. "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
  3. "Complete sequencing and characterization of 21,243 full-length human cDNAs." Nat. Genet. 36:40-45(2004) [PubMed] [Europe PMC] [Abstract]
  4. "Diagnostic exome sequencing in persons with severe intellectual disability."N. Engl. J. Med. 367:1921-1929(2012) [PubMed] [Europe PMC] [Abstract]