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SH3 Domain Binding Protein 5 Like Protein (SH3BP5L)

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SH3 Domain Binding Protein 5 Like Protein (SH3BP5L)
CCC U934
HGNC 29360
MGI 1933124
RGD 1590939
UniProt Q7L8J4
SH3BP5L Belongs to the SH3BP5 family.SH3BP5 encodes a deduced 425-amino acid protein. Northern blot analysis revealed wide expression of a 3.0-kb transcript, with especially prominent expression in testis and ovary. Immunoblot analysis showed that SH3BP5 is expressed as a 70-kD protein. Immunoprecipitation analysis suggested that SH3BP5 interacts with BTK in cells. Mutational and immunoblot analyses showed that amino acids 163 to 193 of SH3BP5 bind most strongly to the SH3 domain of BTK and not with the SH3 domains of a number of other cytoplasmic tyrosine kinases.
Bruton tyrosine kinase (BTK) is a cytoplasmic tyrosine kinase crucial for the maturation of B-lineage cells. BTK deficiency is involved in the pathogenesis of X-linked immunodeficiency.

Organism species: Homo sapiens (Human)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a Recombinant SH3 Domain Binding Protein 5 Like Protein (SH3BP5L) Recombinant Protein Customized Service Offer
Antibodies n/a Monoclonal Antibody to SH3 Domain Binding Protein 5 Like Protein (SH3BP5L) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to SH3 Domain Binding Protein 5 Like Protein (SH3BP5L) Polyclonal Antibody Customized Service Offer
Assay Kits n/a CLIA Kit for SH3 Domain Binding Protein 5 Like Protein (SH3BP5L) CLIA Kit Customized Service Offer
n/a ELISA Kit for SH3 Domain Binding Protein 5 Like Protein (SH3BP5L) ELISA Kit Customized Service Offer

Organism species: Mus musculus (Mouse)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a Recombinant SH3 Domain Binding Protein 5 Like Protein (SH3BP5L) Recombinant Protein Customized Service Offer
Antibodies n/a Monoclonal Antibody to SH3 Domain Binding Protein 5 Like Protein (SH3BP5L) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to SH3 Domain Binding Protein 5 Like Protein (SH3BP5L) Polyclonal Antibody Customized Service Offer
Assay Kits n/a CLIA Kit for SH3 Domain Binding Protein 5 Like Protein (SH3BP5L) CLIA Kit Customized Service Offer
n/a ELISA Kit for SH3 Domain Binding Protein 5 Like Protein (SH3BP5L) ELISA Kit Customized Service Offer

Organism species: Rattus norvegicus (Rat)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a Recombinant SH3 Domain Binding Protein 5 Like Protein (SH3BP5L) Recombinant Protein Customized Service Offer
Antibodies n/a Monoclonal Antibody to SH3 Domain Binding Protein 5 Like Protein (SH3BP5L) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to SH3 Domain Binding Protein 5 Like Protein (SH3BP5L) Polyclonal Antibody Customized Service Offer
Assay Kits n/a CLIA Kit for SH3 Domain Binding Protein 5 Like Protein (SH3BP5L) CLIA Kit Customized Service Offer
n/a ELISA Kit for SH3 Domain Binding Protein 5 Like Protein (SH3BP5L) ELISA Kit Customized Service Offer
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