GPN Loop GTPase 3 (GPN3)

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ATPBD1C; ATP-binding domain 1 family member C

GPN Loop GTPase 3 (GPN3)
GPN3 Belongs to the GPN-loop GTPase family. GTPases (singular GTPase) are a large family of hydrolase enzymes that can bind and hydrolyze guanosine triphosphate (GTP). The GTP binding and hydrolysis takes place in the highly conserved G domain common to all GTPases.
All regulatory GTPases have a common mechanism that enables them to switch a signal transduction chain on and off. Toggling the switch is performed by the unidirectional change of the GTPase from the active, GTP-bound form to the inactive, GDP-bound form by hydrolysis of the GTP through intrinsic GTPase-activity, effectively switching the GTPase off. This reaction is initiated by GTPase-activating proteins (GAPs), coming from another signal transduction pathway.

Organism species: Homo sapiens (Human)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a Recombinant GPN Loop GTPase 3 (GPN3) Recombinant Protein Customized Service Offer
Antibodies n/a Monoclonal Antibody to GPN Loop GTPase 3 (GPN3) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to GPN Loop GTPase 3 (GPN3) Polyclonal Antibody Customized Service Offer
Assay Kits n/a CLIA Kit for GPN Loop GTPase 3 (GPN3) CLIA Kit Customized Service Offer
n/a ELISA Kit for GPN Loop GTPase 3 (GPN3) ELISA Kit Customized Service Offer

Organism species: Mus musculus (Mouse)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a Recombinant GPN Loop GTPase 3 (GPN3) Recombinant Protein Customized Service Offer
Antibodies n/a Monoclonal Antibody to GPN Loop GTPase 3 (GPN3) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to GPN Loop GTPase 3 (GPN3) Polyclonal Antibody Customized Service Offer
Assay Kits n/a CLIA Kit for GPN Loop GTPase 3 (GPN3) CLIA Kit Customized Service Offer
n/a ELISA Kit for GPN Loop GTPase 3 (GPN3) ELISA Kit Customized Service Offer

Organism species: Rattus norvegicus (Rat)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a Recombinant GPN Loop GTPase 3 (GPN3) Recombinant Protein Customized Service Offer
Antibodies n/a Monoclonal Antibody to GPN Loop GTPase 3 (GPN3) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to GPN Loop GTPase 3 (GPN3) Polyclonal Antibody Customized Service Offer
Assay Kits n/a CLIA Kit for GPN Loop GTPase 3 (GPN3) CLIA Kit Customized Service Offer
n/a ELISA Kit for GPN Loop GTPase 3 (GPN3) ELISA Kit Customized Service Offer
  1. "NovelFam3000 -- uncharacterized human protein domains conserved across model organisms."BMC Genomics 7:48-48(2006) [PubMed] [Europe PMC] [Abstract]
  2. "Gene expression profiling in the human hypothalamus-pituitary-adrenal axis and full-length cDNA cloning." Proc. Natl. Acad. Sci. U.S.A. 97:9543-9548(2000) [PubMed] [Europe PMC] [Abstract]
  3. "The secreted protein discovery initiative (SPDI), a large-scale effort to identify novel human secreted and transmembrane proteins: a bioinformatics assessment." Genome Res. 13:2265-2270(2003) [PubMed] [Europe PMC] [Abstract]
  4. "The full-ORF clone resource of the German cDNA consortium."BMC Genomics 8:399-399(2007) [PubMed] [Europe PMC] [Abstract]
  5. "Complete sequencing and characterization of 21,243 full-length human cDNAs." Nat. Genet. 36:40-45(2004) [PubMed] [Europe PMC] [Abstract]
  6. "The finished DNA sequence of human chromosome 12." Nature 440:346-351(2006) [PubMed] [Europe PMC] [Abstract]
  7. "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
  8. "HSP90 and its R2TP/Prefoldin-like cochaperone are involved in the cytoplasmic assembly of RNA polymerase II."Mol. Cell 39:912-924(2010) [PubMed] [Europe PMC] [Abstract]
  9. "Initial characterization of the human central proteome."BMC Syst. Biol. 5:17-17(2011) [PubMed] [Europe PMC] [Abstract]
  10. "Human GTPases associate with RNA polymerase II to mediate its nuclear import."Mol. Cell. Biol. 31:3953-3962(2011) [PubMed] [Europe PMC] [Abstract]