Olfactory Receptor 52Z1 (OR52Z1)

OR52W1 belongs to the G-protein coupled receptor 1 family. A single nucleotide insertion at position Gly-8 in the gene coding for this protein is responsible for functional diversity thus producing a pseudogene.Olfactory receptors interact with odorant molecules in the nose, to initiate a neuronal response that triggers the perception of a smell. The olfactory receptor proteins are members of a large family of G-protein-coupled receptors (GPCR) arising from single coding-exon genes. Olfactory receptors share a 7-transmembrane domain structure with many neurotransmitter and hormone receptors and are responsible for the recognition and G protein-mediated transduction of odorant signals. The olfactory receptor gene family is the largest in the genome. The nomenclature assigned to the olfactory receptor genes and proteins for this organism is independent of other organisms.