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Complete DNA sequence and characterization of a 330-kb VNTR-rich region on chromosome 6q27 that is commonly deleted in ovarian cancer. four novel genes, HGC6.1-4, as well as the known AF-6 gene. None of the deduced products of the novel genes exhibited significant homology to previously known proteins.
HGC6.3 contained a VNTR within a coding exon, each repeat consisting of 42 nucleotides; the predicted 14-amino-acid consensus unit is MTPTVFSSQHTAGG. At least nine different sizes of this VNTR locus were detected among 20 unrelated DNA samples from caucasians. The polymorphic markers and the transcript map documented here may contribute to identification of novel genes or allelic aberrations associated with the development of ovarian cancers.
Organism species: Homo sapiens (Human)
| CATALOG NO. | PRODUCT NAME | APPLICATIONS | |
| Proteins | n/a | Recombinant Chromosome 6 Open Reading Frame 123 (C6orf123) | Recombinant Protein Customized Service Offer |
| Antibodies | n/a | Monoclonal Antibody to Chromosome 6 Open Reading Frame 123 (C6orf123) | Monoclonal Antibody Customized Service Offer |
| n/a | Polyclonal Antibody to Chromosome 6 Open Reading Frame 123 (C6orf123) | Polyclonal Antibody Customized Service Offer | |
| Assay Kits | n/a | CLIA Kit for Chromosome 6 Open Reading Frame 123 (C6orf123) | CLIA Kit Customized Service Offer |
| n/a | ELISA Kit for Chromosome 6 Open Reading Frame 123 (C6orf123) | ELISA Kit Customized Service Offer |
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- "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]